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In article number 2002997, Jonathan O. Martinez, Francesca Taraballi, and co‐workers present a new drug delivery approach, combining mesenchymal stromal cell (MSC) tropism with multistage nano‐vector (MSV) payload delivery. The MSCs act as a “trojan horse,” carrying MSV at the site of inflammation in an efficient manner. The system can transport anti‐inflammatory payloads, conserving local inflammatory...
The emergence of cell‐based therapeutics, specifically the use of mesenchymal stromal/stem cells (MSCs), stands to significantly affect the future of targeted drug delivery technologies. MSCs represent a unique cell type, offering more than only regenerative potential but also site‐specific inflammatory targeting and tissue infiltration. In this study, a versatile multicomponent delivery platform,...
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