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A rapid and sensitive flow injection chemiluminescence (FI–CL) method is described for the determination of 2‐methoxyestradiol (2ME) based on enhancement of the CL intensity from a potassium ferricyanide–calcein system in sodium hydroxide medium. The optimum conditions for the CL emission were investigated. Under optimized conditions, a linear calibration graph was obtained over the range 1.0 × 10...
2‐Methoxyestradiol (2‐ME) is an endogenous metabolite of 17β‐estradiol. In this study, we determined the antitumour activities of 2‐ME on the well‐differentiated EC9706 esophageal carcinoma cells in vitro. 2‐ME had a strong antiproliferative effect on EC9706 cells and caused an increase in the population of apoptotic cells, detected by flow cytometry. A significant number of cells were blocked in...
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