Search results for: Rashid Bashir

Items from 1 to 20 out of 97 results

article

High Sensitivity Graphene Field Effect Transistor‐Based Detection of DNA Amplification

Anurup Ganguli, Vahid Faramarzi, Ariana Mostafa, Michael T. Hwang, more

Advanced Functional Materials > 30 > 28 > n/a - n/a

Enzymatic DNA amplification‐based approaches involving intercalating DNA‐binding fluorescent dyes and expensive optical detectors are the gold standard for nucleic acid detection. As components of a simplified and miniaturized system, conventional silicon‐based ion sensitive field effect transistors (ISFETs) that measure a decrease in pH due to the generation of pyrophosphates during DNA amplification...

article

Simulation and Fabrication of Stronger, Larger, and Faster Walking Biohybrid Machines

Gelson J. Pagan‐Diaz, Xiaotian Zhang, Lauren Grant, Yongdeok Kim, more

Advanced Functional Materials > 28 > 33 > n/a - n/a

article

3D printing for preoperative planning and surgical training: a review

Anurup Ganguli, Gelson J. Pagan-Diaz, Lauren Grant, Caroline Cvetkovic, more

Biomedical Microdevices > 2018 > 20 > 3 > 1-24

Surgeons typically rely on their past training and experiences as well as visual aids from medical imaging techniques such as magnetic resonance imaging (MRI) or computed tomography (CT) for the planning of surgical processes. Often, due to the anatomical complexity of the surgery site, two dimensional or virtual images are not sufficient to successfully convey the structural details. For such scenarios,...

article

Biomimetics: Simulation and Fabrication of Stronger, Larger, and Faster Walking Biohybrid Machines (Adv. Funct. Mater. 23/2018)

Gelson J. Pagan‐Diaz, Xiaotian Zhang, Lauren Grant, Yongdeok Kim, more

Advanced Functional Materials > 28 > 23 > n/a - n/a

This image portrays a top view of three “biobots” in a culture dish covered in media. In article number 1801145, Rashid Bashir and co‐workers use computational modeling to design and optimize their function and performance. These thumb‐sized biohybrid biological machines can generate milli‐Newton range forces when electrically stimulated, and can walk at the surface of the Petri dish for distances...

article

Simulation and Fabrication of Stronger, Larger, and Faster Walking Biohybrid Machines

Gelson J. Pagan‐Diaz, Xiaotian Zhang, Lauren Grant, Yongdeok Kim, more

Advanced Functional Materials > 28 > 23 > n/a - n/a

Advancing biologically driven soft robotics and actuators will involve employing different scaffold geometries and cellular constructs to enable a controllable emergence for increased production of force. By using hydrogel scaffolds and muscle tissue, soft biological robotic actuators that are capable of motility have been successfully engineered with varying morphologies. Having the flexibility of...

article

Robust label-free microRNA detection using one million ISFET array

Anurup Ganguli, Yoshihiko Watanabe, Michael T. Hwang, Jui-Cheng Huang, more

Biomedical Microdevices > 2018 > 20 > 2 > 1-10

Detection of nucleic acid molecules is one of the most pervasive assays in biology, medicine, and agriculture applications. Currently, most comely used DNA/RNA detection platforms use fluorescence labeling and require lab-scale setting for performing the assay. There is a need for developing less expensive, label-free, and rapid detection of biomolecules with minimal utilization of resources. Use...

chapter

Multiplexed detection of infectious diseases with microfluidic loop-mediated isothermal amplification and a smartphone

Fu Sun, Weili Chen, Hojeong Yu, Akid Omob, more

2017 IEEE Healthcare Innovations and Point of Care Technologies (HI-POCT) > 241 - 244

2017 IEEE Healthcare Innovation Point-of-Care Technologies (HI-POCT)

New tools are needed to enable rapid detection, identification, and reporting of infectious viral and microbial pathogens in a wide variety of point-of-care applications that impact human and animal health. We report the design, construction, and characterization of a platform for multiplexed analysis of disease-specific DNA sequences that utilizes a smartphone camera as the sensor in conjunction...

article

Characterization of a 1024×1024 DG-BioFET platform

Carlos Duarte-Guevara, Vikhram Swaminathan, Bobby Reddy, Chin-Hua Wen, more

Sensors and Actuators B: Chemical > 2017 > 250 > C > 100-110

The use of biological field effect transistors (BioFETs) for the detection of biochemical events will yield new sensing systems that are smaller, less expensive, faster, and capable of multiplexing. Here, we present a novel massively parallel dual-gated BioFET (DG-BioFET) platform with over a million transistors in a 7×7mm² array that has all these benefits. Utilizing on-chip integrated circuits for...

article

Evidence of differential mass change rates between human breast cancer cell lines in culture

Elise A. Corbin, Olaoluwa O. Adeniba, Olivia V. Cangellaris, William P. King, more

Biomedical Microdevices > 2017 > 19 > 1 > 1-7

Investigating the growth signatures of single cells will determine how cell growth is regulated and cell size is maintained. The ability to precisely measure such changes and alterations in cell size and cell mass could be important for applications in cancer and drug screening. Here, we measure the mass growth rate of individual benign (MCF-10A), non-invasive (MCF-7), and highly-invasive malignant...

book

Nanopores

Samir M. Iqbal, Rashid Bashir, Springer US

Nanopores: Sensing and Fundamental Biological Interactions examines the emerging research directions surrounding nanopores such as genome sequencing and early disease detection using biomarker identification. Nanopores are nanometer scale holes formed naturally by proteins or cells, and can be used for a variety of applications, including sequencing DNA and detecting harmful chemicals such as anthrax...

article

Design and integration of a problem-based biofabrication course into an undergraduate biomedical engineering curriculum

Ritu Raman, Marlon Mitchell, Pablo Perez-Pinera, Rashid Bashir, more

Journal of Biological Engineering > 2016 > 10 > 1 > 1-8

Background The rapidly evolving discipline of biological and biomedical engineering requires adaptive instructional approaches that teach students to target and solve multi-pronged and ill-structured problems at the cutting edge of scientific research. Here we present a modular approach to designing a lab-based course in the emerging field of biofabrication and biological design, leading to a final...

chapter

HIV-1 IIIB capture from whole blood on magnetic microparticles

Gregory L. Damhorst, Jonathan M. Kooiman, Rashid Bashir

2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) > 5785 - 5788

2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

Viral load quantification is a critical need for HIV management worldwide. However, the diagnostic technologies currently available are too limited by their size and expense to reach many remote and resource-limited populations. Toward the development of techniques which can be leveraged for point-of-care assays, we have investigated affinity capture of whole viruses using magnetic microparticles...

chapter

Solid-State Nanopore Sensors for Nucleic Acid Analysis

Bala Murali Venkatesan, Rashid Bashir

Nanopores > 1-33

Solid-state nanopores are nm sized apertures formed in thin synthetic membranes. These single molecule sensors have been used in a variety of biophysical and diagnostic applications and serve as a potential candidate in the development of cost-effective, next generation DNA sequencing technologies, critical to furthering our understanding of inheritance, individuality, disease and evolution. The versatility...

chapter

Digital Health and Bio-Medical Packaging

Lei Mercado, James K. Carney, Michael J. Ebert, Scott A. Hareland, more

Materials for Advanced Packaging > 681-712

This chapter reviews the healthcare trends and implications, as well as electronic packaging applications in implantable devices, pacing leads, bio-medical sensors, and point-of-care sensors. Each presents unique opportunities and challenges for electronic packaging and materials.

chapter

Nanoelectronic-Based Detection for Biology and Medicine

Samir M. Iqbal, Rashid Bashir

Springer Handbook of Automation > Automation in Medical and Healthcare Systems > 1433-1449

This chapter is a review of the work in nanoelectronic detection of biological molecules and its applications in biology and medicine. About half of the chapter focuses on the methods employed to immobilize deoxyribonucleic acid (DNA) on solid substrates with particular focus on the electronic detection and characterization of DNA. Charge-transfer properties and theories are explained, as such electronic...

article

Effect of Pore-Water Surface Tension on Tensile Strength of Unsaturated Sand

Prateek Jindal, Jitendra Sharma, Rashid Bashir

Indian Geotechnical Journal > 2016 > 46 > 3 > 276-290

Tensile behaviour of unsaturated sand was investigated both experimentally and theoretically. A custom-built direct tension apparatus was employed to perform direct tension tests on unsaturated sand specimens at different saturations levels and packing dry density. An attempt was made to understand the effect of surface tension of wetting liquid and loading rate on the tensile strength. The magnitude...

article

Magnetophoretic-based microfluidic device for DNA Concentration

Sangjo Shim, Jiwook Shim, William R. Taylor, Farhad Kosari, more

Biomedical Microdevices > 2016 > 18 > 2 > 1-8

Nucleic acids serve as biomarkers of disease and it is highly desirable to develop approaches to extract small number of such genomic extracts from human bodily fluids. Magnetic particles-based nucleic acid extraction is widely used for concentration of small amount of samples and is followed by DNA amplification in specific assays. However, approaches to integrate such magnetic particles based capture...

article

3D printing enables separation of orthogonal functions within a hydrogel particle

Ritu Raman, Nicholas E. Clay, Sanjeet Sen, Molly Melhem, more

Biomedical Microdevices > 2016 > 18 > 3 > 1-7

Multifunctional particles with distinct physiochemical phases are required by a variety of applications in biomedical engineering, such as diagnostic imaging and targeted drug delivery. This motivates the development of a repeatable, efficient, and customizable approach to manufacturing particles with spatially segregated bioactive moieties. This study demonstrates a stereolithographic 3D printing...

article

On-chip PMA labeling of foodborne pathogenic bacteria for viable qPCR and qLAMP detection

Paula Duarte-Guevara, Carlos Duarte-Guevara, Akid Ornob, Rashid Bashir

Microfluidics and Nanofluidics > 2016 > 20 > 8 > 1-9

Propidium monoazide (PMA) is a membrane impermeable molecule that covalently bonds to double stranded DNA when exposed to light and inhibits the polymerase activity, thus enabling DNA amplification detection protocols that discriminate between viable and non-viable entities. Here, we present a microfluidic device for inexpensive, fast, and simple PMA labeling for viable qPCR and qLAMP assays. The...

article

Transient Eletronics: Biodegradable Thin Metal Foils and Spin‐On Glass Materials for Transient Electronics (Adv. Funct. Mater. 12/2015)

Seung‐Kyun Kang, Suk‐Won Hwang, Sooyoun Yu, Jung‐Hun Seo, more

Advanced Functional Materials > 25 > 12 > 1904 - 1904

The back cover image shows an array of transient electronic devices on a thin molybdenum foil, designed to dissolve completely in aqueous solutions in a controlled manner. The results presented by J. A. Rogers and co‐workers on page 1789 suggest that biodegradable metal foils can provide robust and practical substrates for new applications such as those in temporary implants for biomedical diagnosis...

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INFONA - science communication portal

Search results for: Rashid Bashir

High Sensitivity Graphene Field Effect Transistor‐Based Detection of DNA Amplification

Simulation and Fabrication of Stronger, Larger, and Faster Walking Biohybrid Machines

3D printing for preoperative planning and surgical training: a review

Biomimetics: Simulation and Fabrication of Stronger, Larger, and Faster Walking Biohybrid Machines (Adv. Funct. Mater. 23/2018)

Simulation and Fabrication of Stronger, Larger, and Faster Walking Biohybrid Machines

Robust label-free microRNA detection using one million ISFET array

Multiplexed detection of infectious diseases with microfluidic loop-mediated isothermal amplification and a smartphone

Characterization of a 1024×1024 DG-BioFET platform

Evidence of differential mass change rates between human breast cancer cell lines in culture

Nanopores

Design and integration of a problem-based biofabrication course into an undergraduate biomedical engineering curriculum

HIV-1 IIIB capture from whole blood on magnetic microparticles

Solid-State Nanopore Sensors for Nucleic Acid Analysis

Digital Health and Bio-Medical Packaging

Nanoelectronic-Based Detection for Biology and Medicine

Effect of Pore-Water Surface Tension on Tensile Strength of Unsaturated Sand

Magnetophoretic-based microfluidic device for DNA Concentration

3D printing enables separation of orthogonal functions within a hydrogel particle

On-chip PMA labeling of foodborne pathogenic bacteria for viable qPCR and qLAMP detection

Transient Eletronics: Biodegradable Thin Metal Foils and Spin‐On Glass Materials for Transient Electronics (Adv. Funct. Mater. 12/2015)

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