The causes of distinct patterns of reduced cortical thickness in the common human epilepsies, detectable on neuroimaging and with important clinical consequences, are unknown. We investigated the underlying mechanisms of cortical thinning using a systems‐level analysis.
Imaging‐based cortical structural maps from a large‐scale epilepsy neuroimaging study were overlaid with highly spatially...
Epilepsy is a common and serious neurological disorder, with many different constituent conditions characterized by their electro clinical, imaging, and genetic features. MRI has been fundamental in advancing our understanding of brain processes in the epilepsies. Smaller‐scale studies have identified many interesting imaging phenomena, with implications both for understanding pathophysiology and...
We use the dynamic electroencephalography–functional magnetic resonance imaging (EEG‐fMRI) method to incorporate variability in the amplitude and field of the interictal epileptic discharges (IEDs) into the fMRI analysis. We ask whether IED variability analysis can (a) identify additional activated brain regions during the course of IEDs, not seen in standard analysis; and (b) demonstrate...
The aim of this report is to present our clinical experience of electroencephalography–functional magnetic resonance imaging (EEG‐fMRI) in localizing the epileptogenic focus, and to evaluate the clinical impact and challenges associated with the use of EEG‐fMRI in pharmacoresistant focal epilepsy.
We identified EEG‐fMRI studies (n = 118) in people with focal epilepsy performed...
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