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DNA‐origami nanodevices are embedded on the membrane of two cells by Jonathan W. Song, Carlos E. Castro, and co‐workers in article number 1703632. The devices are anchored to the cell via a DNA base‐pairing attachment to a cholesterol‐labeled DNA strand embedded in the membrane. The two pairs of nanostructures (shown here on the right) mediate adhesion between the cells via a sequence‐specific DNA...
A specific and reversible method is reported to engineer cell‐membrane function by embedding DNA‐origami nanodevices onto the cell surface. Robust membrane functionalization across epithelial, mesenchymal, and nonadherent immune cells is achieved with DNA nanoplatforms that enable functions including the construction of higher‐order DNA assemblies at the cell surface and programed cell–cell adhesion...
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