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We propose an approach for determining the alveolar–mean capillary oxygen (O 2 ) partial pressure gradient to evaluate the efficiency of O 2 equilibration between alveolar space and pulmonary capillary blood. For this purpose, measurements of the pulmonary [ 15 N]nitric oxide diffusing capacity are to be interpolated into the recording of O 2 consumption. We expect...
Because lung nitric oxide (NO) diffusing capacity (D L ) represents alveolar-capillary gas diffusion, we queried as to whether disturbances of pulmonary gas exchange in interstitial lung disease (ILD) are appropriately reflected by using NO. In this pilot study, we applied the 15 N-labeled stable isotope 15 NO (relative abundance 0.37% of total NO) in order to ignore...
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