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Bevacizumab (BEV, Avastin ® ) produces durable objective radiological responses of 20–26 %, median response durations of 16–18 weeks, and median overall survival (mOS) of 31–40 weeks. While the use of BEV is well-established, the lack of dose–response studies in glioblastoma (GBM) patients raises the question whether current dosing practice is optimal. As a result of differing approaches...
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