Search results for: Palmina Petruzzo

Items from 1 to 20 out of 23 results

article

Graft vasculopathy in upper extremity allotransplantation: Results of a retrospective high‐resolution ultrasonographic study

Palmina Petruzzo, Stephane Luong, Jean Kanitakis, Claudia Sardu, more

Clinical Transplantation > 35 > 1 > n/a - n/a

Graft vasculopathy (GV) is the most severe pathologic change of chronic rejection in vascularized composite allotransplantation. Since 2012, the intimal media thickness (IMT) of radial and ulnar arteries was annually monitored by high‐resolution ultrasonography in seven bilateral upper extremity transplant (UET) patients. We also investigated the IMT of seven matched healthy subjects (controls). No...

article

Nail changes in upper extremity allotransplantation: onychomadesis as the presenting sign of allograft rejection – a retrospective study

Jean Kanitakis, Palmina Petruzzo, Robert Baran, Aram Gazarian, more

Transplant International > 33 > 10 > 1274 - 1281

Upper extremity allotransplantation (UEA) is the more common type of vascularized composite allotransplantation of which more than 80 patients have benefited worldwide. These allografts include – along with the skin – the nail unit, a specialized epithelial appendage which may be the target of graft rejection. We report an UEA recipient who developed, as an initial manifestation of graft rejection,...

article

Infections after upper extremity allotransplantation: a worldwide population cohort study, 1998‐2017

Anne Conrad, Palmina Petruzzo, Jean Kanitakis, Aram Gazarian, more

Transplant International > 32 > 7 > 693 - 701

Risk‐to‐benefit analysis of upper extremity allotransplantation (UEA) warrants a careful assessment of immunosuppression‐related complications. This first systematic report of infectious complications after UEA aimed to compare incidence and pattern of infections to that observed after kidney transplantation (KT). We conducted a matched cohort study among UEA and KT recipients from the International...

article

Vascularized composite allotransplantation – a Council of Europe position paper

Marie Thuong, Palmina Petruzzo, Luis Landin, Beatriz Mahillo, more

Transplant International > 32 > 3 > 233 - 240

After more than 120 hand‐upper extremity and 37 face transplant procedures performed worldwide, vascularized composite allotransplantation (VCA) now falls under the scope of organ transplant legislation in Europe and the United States. While in the USA, VCA has been considered as standard care since 2014, VCA in Europe is still performed through clinical research trials, except in United Kingdom....

article

Hypothermic pulsatile preservation of kidneys from uncontrolled deceased donors after cardiac arrest – a retrospective study

Xavier Matillon, Fabrice Danjou, Palmina Petruzzo, Olivier Thaunat, more

Transplant International > 30 > 12 > 1284 - 1291

Kidneys from uncontrolled donors after cardiac arrest (uDCD) suffer from a period of warm ischemia between cardiac arrest and cold flushing. Aim of the study was to evaluate renal outcomes of uDCD kidneys selected on the basis of renal Resistance Index (RI) and its influence on graft function and survival. The study included 44 kidneys procured from 26 uDCD starting 1.1.2006 until 12.31.2013. The...

article

Report (2017) of the International Registry on Hand and Composite Tissue Allotransplantation (IRHCTT)

Palmina Petruzzo, Claudia Sardu, Marco Lanzetta, Jean Michel Dubernard

Current Transplantation Reports > 2017 > 4 > 4 > 294-303

Purpose of Review Analysis of all upper extremity (UET) and face allotransplantations (FT) reported to the International Registry on Hand and Composite Tissue Transplantation (IRHCTT) by May 2017. Recent Findings The IRHCTT includes 66 cases of UET (18 unilateral and 38 bilateral) and 30 of FT. Acute and chronic rejections were reported in the presence of immunosuppression. Complications similar...

chapter

International Registry of Face Transplantation

Palmina Petruzzo, Marco Lanzetta, Jean Michel Dubernard

The Know-How of Face Transplantation > Future Directions in Face Transplantation > 411-415

The International Registry on Hand and Composite Tissue Transplantation (IRHCTT) was founded in 2002 and its purpose was to collect detailed information from every case of hand and face transplantation providing a unique opportunity for the teams to share their experiences and to keep abreast of the latest developments. The registry of face transplantation presents some peculiar characteristics as...

article

Bilateral hand transplantation: Functional benefits assessment in five patients with a mean follow-up of 7.6 years (range 4–13 years)

Laurence Bernardon, Aram Gazarian, Palmina Petruzzo, Tara Packham, more

Journal of Plastic, Reconstructive & Aesthetic Surgery > 2015 > 68 > 9 > 1171-1183

Between January 2000 and July 2009, five adults who had suffered bilateral traumatic below-elbow amputations, received bilateral hand-forearm allografts performed by the Lyon team. We report the functional benefits achieved over a mean follow-up period of 7.6 years (range 4–13 years), up to December 31st, 2013. Clinical measurement is hampered by the lack of specific validated assessment tools, obliging...

article

Immunological Challenges in Vascularised Composite Allotransplantation

Emmanuel Morelon, Jean Kanitakis, Palmina Petruzzo, Lionel Badet, more

Current Transplantation Reports > 2015 > 2 > 3 > 276-283

Vascularised composite allotransplantation (VCA) is a new field in transplantation aiming to improve disabled patients’ quality of life. Two tissues appear to play an important role in the immune response: the skin, which is highly immunogenic and the main target of T-lymphocyte-mediated acute rejection, and the vessels, which are targeted by the humoral arm of recipient’s immune response, which lead...

article

Graft vasculopathy in the skin of a human hand allograft: implications for diagnosis of rejection of vascularized composite allografts

Jean Kanitakis, Georgia Karayannopoulou, Marco Lanzetta, Palmina Petruzzo

Transplant International > 27 > 11 > e118 - e123

Whereas vascularized composite allografts often undergo acute rejections early in the postgraft period, rejection manifesting with severe vascular changes (graft vasculopathy) has only been observed on three occasions in humans. We report a hand‐allografted patient who developed severe rejection following discontinuation of the immunosuppressive treatment. It manifested clinically with erythematous...

article

Influence of allograft weight to recipient bodyweight ratio on outcome of cadaveric renal transplantation

Ricardo Codas, Fabrice Danjou, Celine Dagot, Xavier Martin, more

Nephrology > 19 > 7 > 420 - 425

AimOne of the factors that may affect survival and function of kidney graft is its functional mass. MethodsIn a prospective study, we investigated the impact of the ratio between donor kidney weight in grams and recipient bodyweight in kilograms (DKW/RBW) on creatinine clearance, inulin clearance, and proteinuria: 154 kidneys from deceased donors were weighed and the mean kidney weight was 227 ±...

article

Dual kidney transplantation from uncontrolled deceased donors after cardiac arrest: A possible option

William Hanf, Palmina Petruzzo, Vannary Meas‐Yedid, Julien Berthiller, more

International Journal of Urology > 21 > 2 > 204 - 206

Organ shortage is a major problem in organ transplantation. For this reason, transplantation teams have found it necessary to revisit their organ acceptance criteria. Uncontrolled deceased donors after cardiac arrest could increase the donor pool by 20%, but at the same time there is a greater risk of delayed graft function and primary non‐function. Dual kidney transplantation is an option when single...

article

Alopecia areata in a composite tissue (hand) allograft recipient following graft rejection

Jean Kanitakis, Palmina Petruzzo, Emmanuel Morelon, Lionel Badet

Transplant International > 25 > 11 > e117 - e119

article

Self‐renewal capacity of human epidermal Langerhans cells: observations made on a composite tissue allograft

Jean Kanitakis, Emmanuel Morelon, Palmina Petruzzo, Lionel Badet, more

Experimental Dermatology > 20 > 2 > 145 - 146

Abstract: Epidermal Langerhans cells (LC) are dendritic, antigen‐presenting cells residing within mammalian epidermis and mucosal epithelia. When massively depleted, they are replaced by cells of bone‐marrow origin. However, their renewal within normal skin under steady‐state conditions is not precisely known. We observed that epidermal LC within a human hand allograft remain stable in the long term...

article

Renal Ischemic Preconditioning Improves Recovery of Kidney Function and Decreases α-Smooth Muscle Actin Expression in a Rat Model

Marc Olivier Timsit, Rudy Gadet, Hassen Ben Abdennebi, Ricardo Codas, more

The Journal of Urology > 2008 > 180 > 1 > 388-391

We determined the role of ischemic preconditioning on renal function and histology in a rat model.A total of 34 Sprague-Dawley rats (Janvier Laboratories, Le Genet-St-Isle, France) were divided into 6 groups, including sham operation, ischemic preconditioning alone (5 minutes of bilateral ischemia followed by 5 minutes of reperfusion for 3 cycles), ischemia alone (60 minutes of bilateral renal pedicle...

article

Hand Transplantation: The Milan Experience

Marco Lanzetta, Roberta Nolli, Giovannni Vitale, Francesca Magni, more

Comparative Professional Pedagogy > 2007 > 79 > 12 > 762-772

The authors describe the most critical aspects of transplantation of the hand. Three successful cases are presented from the Italian Hand Transplantation National Program. The key issues of this new type of surgical reconstruction for major amputations are selection criteria of suitable candidates, technical aspects of surgery, postoperative regime and functional rehabilitation. Other important aspects...

article

Hand Transplantation: The Milan Experience

Marco Lanzetta, Roberta Nolli, Giovannni Vitale, Francesca Magni, more

Polish Journal of Surgery > 2007 > 79 > 12 > 762-772

article

Second Report (1998–2006) of the International Registry of Hand and Composite Tissue Transplantation

Marco Lanzetta, Palmina Petruzzo, Jean Michel Dubernard, Raimund Margreiter, more

Transplant Immunology > 2007 > 18 > 1 > 1-6

Since May 2002 all groups performing hand transplantations have supplied detailed information to the International Registry on Hand and Composite Tissue Transplantation. This report provides a review of all hand transplants performed to date.From September 1998 to February 2006 eighteen male patients underwent 24 hand/forearm/digit transplantations (eleven unilateral and four bilateral hand transplantations,...

article

Effect of IGL-1, a new preservation solution, on kidney grafts (a pre-clinical study)

Lionel Badet, Hassen Abdennebi, Palmina Petruzzo, Brigitte McGregor, more

Transplant International > 2005 > 17 > 12 > 815-821

Ischemia-reperfusion injury conditions short-term and long-term graft function. The effects of the inversion of K⁺ and Na⁺ concentrations and substitution with polyethylene glycol for hydroxyethyl starch in University of Wisconsin (K-UW) solution were evaluated in isolated perfused rat kidneys and in autotransplanted pig kidneys. In the rat model kidneys were cold-stored for 24 h in K-UW or Na-UW...

article

Influence of pancreas allograft venous drainage on kidney and pancreas acute rejection rate

Lionel Badet, Marwan Dawahra, Palmina Petruzzo, Nicole Lefrançois, more

European Urology Supplements > 2002 > 1 > 1 > 16

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Search results for: Palmina Petruzzo

Graft vasculopathy in upper extremity allotransplantation: Results of a retrospective high‐resolution ultrasonographic study

Nail changes in upper extremity allotransplantation: onychomadesis as the presenting sign of allograft rejection – a retrospective study

Infections after upper extremity allotransplantation: a worldwide population cohort study, 1998‐2017

Vascularized composite allotransplantation – a Council of Europe position paper

Hypothermic pulsatile preservation of kidneys from uncontrolled deceased donors after cardiac arrest – a retrospective study

Report (2017) of the International Registry on Hand and Composite Tissue Allotransplantation (IRHCTT)

International Registry of Face Transplantation

Bilateral hand transplantation: Functional benefits assessment in five patients with a mean follow-up of 7.6 years (range 4–13 years)

Immunological Challenges in Vascularised Composite Allotransplantation

Graft vasculopathy in the skin of a human hand allograft: implications for diagnosis of rejection of vascularized composite allografts

Influence of allograft weight to recipient bodyweight ratio on outcome of cadaveric renal transplantation

Dual kidney transplantation from uncontrolled deceased donors after cardiac arrest: A possible option

Alopecia areata in a composite tissue (hand) allograft recipient following graft rejection

Self‐renewal capacity of human epidermal Langerhans cells: observations made on a composite tissue allograft

Renal Ischemic Preconditioning Improves Recovery of Kidney Function and Decreases α-Smooth Muscle Actin Expression in a Rat Model

Hand Transplantation: The Milan Experience

Hand Transplantation: The Milan Experience

Second Report (1998–2006) of the International Registry of Hand and Composite Tissue Transplantation

Effect of IGL-1, a new preservation solution, on kidney grafts (a pre-clinical study)

Influence of pancreas allograft venous drainage on kidney and pancreas acute rejection rate

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