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Acute thrombosis is a leading cause of mortality and morbidity worldwide. Pharmacological thrombolysis relies on plasminogen activators (PAs), which are associated with major side effects including potentially fatal bleeding. Alternative therapeutic options that do not rely on PAs are urgently required. Here, the efficacy of targeted photothermal therapy is evaluated for thrombolysis using liposomes...
Atherosclerosis is a major cause of mortality and morbidity worldwide. Left undiagnosed and untreated, atherosclerotic plaques can rupture and cause cardiovascular complications such as myocardial infarction and stroke. Atherosclerotic plaques are composed of lipids, including oxidized low‐density lipoproteins and cholesterol crystals, and immune cells, including macrophages. 2‐Hydroxypropyl‐beta‐cyclodextrin...
Atherosclerosis Imaging and Therapy
In article number 2200967, Xiaowei Wang, Karlheinz Peter, and co‐workers show that theranostic nanoparticles made of air can deliver a near‐infrared fluorescence dye, cyclodextrin, to be used as a contrast agent for ultrasound and fluorescence imaging and as ultrasound‐responsive anti‐atherosclerotic drug, achieving reduction of cholesterol in plaques after ingestion...
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