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Larrea nitida Cav. (LNC), which belongs to the family Zygophyllaceae, is widely indigenous and used in South America to treat various pathological conditions. It contains the antioxidant and antiinflammatory but toxic nordihydroguaiaretic acid (NDGA) as well as O‐methylated metabolite of NDGA (MNDGA) as bioactive compounds. The hepatic metabolism‐based toxicological potential of extracts of LNC (LNE),...
Phytoestrogens are selective estrogen receptor modulators (SERMs) with potential for use in hormone replacement therapy (HRT) to relieve peri/postmenopausal symptoms. This study was aimed at elucidating the molecular mechanisms underlying the SERM properties of the extract of Korean‐grown Opuntia ficus‐indica (KOFI). The KOFI extract induced estrogen response element (ERE)‐driven transcription in...
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