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Transforming growth factor-β1 (TGF-β1) has been used as a biomarker in disorders associated with pathologic fibrosis. However, plasma TGF-β1 assessment is confounded by the significant variation in reported normal values, likely reflecting variable release of the large pool of platelet TGF-β1 after blood drawing. Moreover, current assays measure only total TGF-β1, which is dominated by the latent...
ObjectivePLGF, a VEGF‐A related protein, mediates collateral enlargement via monocytes but plays little role in capillary proliferation. In contrast, VEGF‐A mediates both collateral enlargement and capillary proliferation. PLGF has been less thoroughly studied than VEGF‐A, and questions remain regarding its regulation and function. Therefore, our goal was to characterize the expression of PLGF by...
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