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Background
Cognitive impairment is common in neurological presentations of Wilson's disease (WD). Various domains can be affected, and subclinical deficits have been reported in patients with hepatic presentations. Associations with imaging abnormalities have not been systematically tested.
Objective
The aim was to determine the neuroanatomical basis for cognitive deficits in WD.
Methods
We performed...
Background
Outcomes are unpredictable for neurological presentations of Wilson's disease (WD). Dosing regimens for chelation therapy vary and monitoring depends on copper indices, which do not reflect end‐organ damage.
Objective
To identify a biomarker for neurological involvement in WD.
Methods
Neuronal and glial‐specific proteins were measured in plasma samples from 40 patients and 38 age‐matched...
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