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Background: The processing of proprotein convertase (PC)-mediated neuropeptide plays a very important role in carcinogenesis and tumor proliferation. Aim: To investigate proneuropeptide processing mechanism in tumorigenesis and tumor proliferation. Materials and methods: The expression and processing profiles of PC1, carboxypeptidase E (CPE), PC2, GHRH, or neuropeptide Y (NPY) gene and protein level...
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