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Background & Aims
BCAT1 initiates the catabolism of branched‐chain amino acids. Here, we investigated the function of BCAT1 and its transcriptional regulatory mechanism in hepatocellular carcinoma (HCC).
Methods
RNASeq was used to evaluate BCAT1 mRNA levels in HCC and normal matched specimens. After the exogenous expression of BCAT1 in BEL‐7404 cells and the suppression of endogenous BCAT1...
Background Bone marrow-derived stem cells (BMSCs) are locally adjacent to the tumor tissues and may interact with tumor cells directly. The purpose of this study was to explore the effects of BMSCs on the proliferation and invasion of osteosarcoma cells in vitro and the possible mechanism involved. Methods BMSCs were co-cultured with osteosarcoma cells, and CCK-8...
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