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miR‐143 is a tumor suppressor miRNA which its downregulation is frequently reported in colorectal cancer (CRC). This miRNA is a negative regulator of K‐RAS, c‐MYC, BCL‐2, and MMP‐9 genes which are engaged in tumor growth and metastasis. In the present study, miR‐143 restoration was performed by transfection of the pCMV‐miR‐143 vector into the SW‐480 CRC cells. Subsequently, alterations in proliferative...