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Frondoside A is a pentaoside having an acetyl moiety at the aglycon ring and xylose as a third monosaccharide residue. Cucumarioside A 2 -2 is a pentaoside having glucose as a third monosaccahride unit. We compared the effects of frondoside A and A 2 -2 for cell death-inducing capability with close attention paid to structure–activity relationships. Both frondoside A and A 2 ...
We recently showed that some of the enzymes underpinning cellulose solubilization by Ruminococcus albus 8 lack the conventional type of dockerin module characteristic of cellulosomal proteins and instead, bear an ''X'' domain of unknown function at their C-termini. We have now subcloned and expressed six X domains and showed that five of them bind to xylan, chitin, microcrystalline and phosphoric-acid...
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