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Ganoderma is classified as a top grade traditional Chinese medicine for promoting human health by regulating ‘vital energy’. Its potency towards metabolism and energy homeostasis, particularly, metabolic adaptations of adipocytes, needs to be re‐evaluated through an evidence‐based study. Here, the triterpenoid‐rich Ganoderma tsugae ethanol extract (GTEE) was found to contribute towards adipogenesis...