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Objective
Sudden unexpected death in epilepsy (SUDEP) is a major outcome of cardiac dysfunction in patients with epilepsy. In continuation of our previous work, the present study was envisaged to explore the key regulators responsible for cardiac damage associated with chronic seizures using whole transcriptome and proteome analysis in a rat model of temporal lobe epilepsy.
Methods
A standard lithium‐pilocarpine...
This study reports a thermostable Cu, Zn superoxide dismutase (SOD) obtained from a high-altitude plant Caragana jubata (Cj-Cu, Zn SOD). The expression of Cj-Cu, Zn SOD in Escherichia coli followed by purification yielded a 17.5kDa protein with a specific activity of 1547±39 units/mg of protein at 0°C. The enzyme (i) functioned across a temperature range of −10 to +80°C with optimum activity at 0–4°C;...
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