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This review presents the data on clinical presentation at diagnosis in 1564 patients included in the European Registry on Cushing's syndrome (ERCUSYN), of whom 1045 (67%) had pituitary‐dependent Cushing's syndrome (CS) (PIT‐CS), 385 (25%) had adrenal dependent CS (ADR‐CS) and 89 (5%) had ectopic adrenocorticotropic hormone syndrome (ECT‐CS). The most frequent symptoms in the overall series were weight...
Objective
Hypercortisolism in Cushing's syndrome (CS) is associated with impaired health‐related quality of life (HRQoL), which may persist despite remission. We used the data entered into the European Registry on Cushing's syndrome (ERCUSYN) to evaluate if patients with CS of pituitary origin (PIT‐CS) have worse HRQoL, both before and after treatment than patients with adrenal causes (ADR‐CS).
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