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In order to find novel antiplatelet drugs for the treatment of ischemic stroke, a series of 3‐butylphthalide derivatives containing isopentenylphenol moiety were designed, synthesized and characterized with spectroscopic analyses. The in vitro antiplatelet activity results indicated that compound 3 better inhibited the arachidonic acid (AA) induced platelet aggregation than aspirin (ASP) and 3‐butylphthalide...
In order to discover novel potential antifungal agents, a series of 6‐substituted 3‐butylphthalide derivatives were designed, synthesized and evaluated for their antifungal activities against nine phytopathogenic fungi. Preliminary bioassay tests showed that five 3‐butylphthalide derivatives exhibited more potent antifungal activities than hymexazol at the concentration of 50 μg/mL. Especially, 3‐butyl‐6‐nitro‐2‐benzofuran‐1(3...
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