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Background
Alopecia areata (AA) is an autoimmune skin disease characterized by abnormal levels of several cytokines, such as interferon alpha (IFN‐α) and tumor necrosis factor‐alpha (TNF‐α), which are T‐helper type 1 cytokines that have important roles in the pathogenesis of AA. The aim of our study was to correlate circulating IFN‐α and TNF‐α levels with disease severity, activity, and clinical...
Vitamin D deficiency has been linked with different health problems including male infertility. Its function is mediated by the vitamin D receptor, which acts as a transcription factor. Epigenetic mechanisms such as DNA methylation may affect the vitamin D receptor gene and result in gene silencing. The present study aimed to assess serum vitamin D level and seminal methylation of vitamin D receptor...
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