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Two artificial neural network (ANN)‐based algorithms for allergenicity prediction were developed and tested. The first algorithm consists of three steps. Initially, the protein sequences are described by amino acid principal properties as hydrophobicity, size, relative abundance, helix and β‐strand forming propensities. Second, the generated strings of different length are converted into vectors with...
Allergy is an overreaction by the immune system to a previously encountered, ordinarily harmless substance —typically proteins—resulting in skin rash, swelling of mucous membranes, sneezing or wheezing, or other abnormal conditions. The use of modified proteins is increasingly widespread: their presence in food, commercial products, such as washing powder, and medical therapeutics and diagnostics,...
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