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Background Normobaric oxygen therapy is frequently applied in neurocritical care, however, whether supplemental FiO 2 has beneficial cerebral effects is still controversial. We examined in patients with severe traumatic brain injury (TBI) the effect of incremental FiO 2 on cerebral excitotoxicity, quantified by cerebral microdialysis (CMD) glutamate. Methods...
Background Sedation and therapeutic hypothermia (TH) delay neurological responses and might reduce the accuracy of clinical examination to predict outcome after cardiac arrest (CA). We examined the accuracy of quantitative pupillary light reactivity (PLR), using an automated infrared pupillometry, to predict outcome of post-CA coma in comparison to standard PLR, EEG, and somato-sensory evoked potentials...
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