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A ribozyme is an RNA enzyme that can catalyze a biochemical reaction. The ribozyme is considered as one of the metalloenzymes because a ribozyme requires a metal ion for a catalytic function and are very sensitive to species and concentration of metal ions. However, little is known about combined effect of the metal ions on the ribozyme reaction. Here, we have investigated the combined effect of...
Lead-dependent ribozyme (leadzyme) is a ribozyme working with Pb 2+ . In this paper, we have investigated the combined effect of metal ions, especially rare earth ions, on the cleavage reaction by the leadzyme. As a result, it was observed that although only a rare earth ion or another divalent ion except Pb 2+ did not play a role as the catalyst, the addition of a rare...
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