Search results for: Rafael López

Items from 1 to 20 out of 252 results

article

Classification and Construction of Minimal Translation Surfaces in Euclidean Space

Thomas Hasanis, Rafael López

Results in Mathematics > 2020 > 75 > 1 > 1-22

A translation surface of Euclidean space $${\mathbb {R}}^3$$ R3 is the sum of two regular curves $$\alpha $$ α and $$\beta $$ β , called the generating curves. In this paper we classify the minimal translation surfaces of $${\mathbb {R}}^3$$ R3 and we give a method of construction of explicit examples. Besides the plane and the minimal surfaces of Scherk type, it is proved that up to reparameterizations...

article

Patient preference for oral chemotherapy in the treatment of metastatic breast and lung cancer

Eva María Ciruelos, María Nieves Díaz, María Dolores Isla, Rafael López, more

European Journal of Cancer Care > 28 > 6 > n/a - n/a

Objectives Although new therapies against metastatic cancer have been developed in recent decades, chemotherapy is still an important treatment option. Prolonged treatment and side‐effects are often discouraging for patients, and in many cases, therapy is only palliative, not curative. This study explores patient preference for oral or intravenous (IV) chemotherapy in the treatment of metastatic...

article

Ultra-Small Platinum Nanoparticles with High Catalytic Selectivity Synthesized by an Eco-friendly Method Supported on Natural Hydroxyapatite

S. A. Gama-Lara, R. Natividad, A. R. Vilchis-Nestor, Rafael López-Castañares, more

Catalysis Letters > 2019 > 149 > 12 > 3447-3453

The biosynthesis of Pt-nanoparticles (Pt NPs) supported on bovine bone powder was conducted by an environmentally friendly method that consists on immersing bovine bone powder into a Pt⁴⁺ metal ion solution at room temperature, atmospheric pressure and subsequent reduction by Heterotheca inuloides. It is worth pointing out that a calcination process is not required for the synthesis of this catalyst...

article

Exosome-mimetic nanoplatforms for targeted cancer drug delivery

Abi J. Vázquez-Ríos, Ángela Molina-Crespo, Belén L. Bouzo, Rafael López-López, more

Journal of Nanobiotechnology > 2019 > 17 > 1 > 1-15

Background Lack of effective tumor-specific delivery systems remains an unmet clinical challenge for successful translation of innovative therapies, such as, therapeutic oligonucleotides. In the past decade, exosomes have been suggested to be ideal drug delivery systems with application in a broad range of pathologies including cancer, due to their organotropic properties. Tumor-derived exosomes,...

article

Association of GSTP1 and ERCC1 polymorphisms with toxicity in locally advanced head and neck cancer platinum‐based chemoradiotherapy treatment

Goretti Duran, Santiago Aguín, Raquel Cruz, Francisco Barros, more

Head & Neck > 41 > 8 > 2704 - 2715

Background Platinum‐based chemoradiotherapy (CRT) is the standard treatment for locally advanced head and neck squamous‐cell carcinomas (HNSCC), and most patients experience serious toxicities. The aim of this study was to investigate the association between candidate genes involved in radiation/platinum pathways and acute toxicity of CRT to determine the predictive value of these polymorphisms for...

article

The role of clonal communication and heterogeneity in breast cancer

Ana Martín-Pardillos, Ángeles Valls Chiva, Gemma Bande Vargas, Pablo Hurtado Blanco, more

BMC Cancer > 2019 > 19 > 1 > 1-26

Background Cancer is a rapidly evolving, multifactorial disease that accumulates numerous genetic and epigenetic alterations. This results in molecular and phenotypic heterogeneity within the tumor, the complexity of which is further amplified through specific interactions between cancer cells. We aimed to dissect the molecular mechanisms underlying the cooperation between different clones. Methods...

article

LESM—An object‐oriented MATLAB program for structural analysis of linear element models

Rafael Lopez Rangel, Luiz Fernando Martha

Computer Applications in Engineering Education > 27 > 3 > 553 - 571

This paper describes the implementation of a MATLAB program based on the Object Oriented Programming paradigm for linear‐elastic analysis of one‐dimensional element models using a conventional displacement‐based procedure. The main objective is the development of an educational tool on matrix structural analysis with a didactic and well‐documented open source code, which allows any user to implement...

article

Presence and Spatial Distribution of Polynuclear Aromatic Hydrocarbons (PAHs) in Groundwater of Merida City, Yucatan, Mexico

Rafael López-Macias, Víctor Cobos-Gasca, Diana Cabañas-Vargas, Jaime Rendón von Osten

Bulletin of Environmental Contamination and Toxicology > 2019 > 102 > 4 > 538-543

The karstic aquifer of Yucatan features a high permeability, therefore, all contaminants placed in the soil surface, can reach it through infiltration along with the rain water. The purpose of the present study is to determine the spatial distribution of the aromatic hydrocarbons in the underground water of Merida City. Fifty wells inside the city were sampled. The sampling took place during the dry...

article

CTCs‐derived xenograft development in a triple negative breast cancer case

Tais Pereira‐Veiga, Manuel Abreu, Diego Robledo, Xavier Matias‐Guiu, more

International Journal of Cancer > 144 > 9 > 2254 - 2265

Triple‐negative breast cancer (TNBC) is characterized by high rates of metastasis and no available molecular targets. CTCs derived xenografts (CDX) have demonstrated to be a promising tool for understanding cancer biology. In our study, a CDX from a TNBC patient was developed for the first time. After CDX characterization, WNT signaling was found as the main mechanism related with this tumor biology...

article

Surfaces with a canonical principal direction and prescribed mean curvature

Rafael López, Gabriel Ruiz-Hernández

Annali di Matematica Pura ed Applicata ( 01923 -) > 2019 > 198 > 4 > 1471-1479

A surface in Euclidean space has a canonical principal direction with respect to a fixed direction $${{\mathbf {d}}}$$ d if its tangent part $${{\mathbf {d}}}^\top $$ d ⊤ is a principal direction along the surface. In this paper, we classify all such surfaces with prescribed mean curvature given as an affine function of one of the following three functions: the height function,...

article

Food addiction and impaired executive functions in women with obesity

Trevor Steward, Gemma Mestre‐Bach, Cristina Vintró‐Alcaraz, María Lozano‐Madrid, more

European Eating Disorders Review > 26 > 6 > 574 - 584

Background Individuals with obesity (OB) often report suffering from addiction‐like symptoms. As in addictions, deficits in executive function domains, such as decision‐making and sustained attention, are found in OB. No study to date has examined the associations between food addiction, OB, and neuropsychological performance. Method Thirty‐three adult women with OB and 36 healthy weight controls...

article

Food addiction and preoperative weight loss achievement in patients seeking bariatric surgery

Fernando Guerrero Pérez, Jéssica Sánchez‐González, Isabel Sánchez, Susana Jiménez‐Murcia, more

European Eating Disorders Review > 26 > 6 > 645 - 656

Introduction Evidence suggests that food addiction (FA) is prevalent among individuals with obesity seeking bariatric surgery (BS), but there is no evidence about whether FA is a predictor of weight loss (WL). We aimed to analyse the prevalence of FA in patients with obesity seeking BS and to examine whether FA could predict WL following dietary intervention before surgery. Method The study included...

article

2018 Annual Report of the European Liver Transplant Registry (ELTR) – 50‐year evolution of liver transplantation

René Adam, Vincent Karam, Valérie Cailliez, John G. O Grady, more

Transplant International > 31 > 12 > 1293 - 1317

The purpose of this registry study was to provide an overview of trends and results of liver transplantation (LT) in Europe from 1968 to 2016. These data on LT were collected prospectively from 169 centers from 32 countries, in the European Liver Transplant Registry (ELTR) beginning in 1968. This overview provides epidemiological data, as well as information on evolution of techniques, and outcomes...

article

The Dirichlet problem for the $$\alpha $$ α -singular minimal surface equation

Rafael López

Archiv der Mathematik > 2019 > 112 > 2 > 213-222

Let $$\Omega \subset \mathbb {R}^n$$ Ω ⊂ R n be a bounded mean convex domain. If $$\alpha <0$$ α < 0 , we prove the existence and uniqueness of classical solutions of the Dirichlet problem in $$\Omega $$ Ω for the $$\alpha $$ α -singular minimal surface equation with arbitrary continuous boundary data.

article

Efficient algorithm for expanding theoretical electron densities in canterakis–zernike functions

Gabriel A. Urquiza‐Carvalho, Gerd B. Rocha, Rafael López

Journal of Computational Chemistry > 39 > 24 > 2022 - 2032

An algorithm for the efficient computation of Canterakis–Zernike moments of theoretically computed molecular electron densities and rotationally invariant Fingerprint indices derived from them is reported. The algorithm is suitable for any density expressed in terms of Gaussian‐ or Slater‐type functions within the Linear Combination of Atomic Orbitals framework at any level of computation. Electron...

article

Compact $$\lambda $$ λ -translating Solitons with Boundary

Rafael López

Mediterranean Journal of Mathematics > 2018 > 15 > 5 > 1-15

A $$\lambda $$ λ -translating soliton with density vector $$\mathbf {v}$$ v is a surface $$\varSigma $$ Σ in Euclidean space $$\mathbb {R}^3$$ R3 whose mean curvature H satisfies $$2H=2\lambda +\langle N,\mathbf {v}\rangle $$ 2H=2λ+⟨N,v⟩ , where N is the Gauss map of $$\varSigma $$ Σ . In this article, we study the shape of a compact $$\lambda $$ λ -translating soliton in terms of its boundary...

article

Some geometric properties of translating solitons in Euclidean space

Rafael López

Journal of Geometry > 2018 > 109 > 3 > 1-15

A translating soliton is a surface in Euclidean space $$\mathbb {R}^3$$ R3 that is minimal for a log-linear density $$\phi (x,y,z)=\alpha x+\beta y+\gamma y$$ ϕ(x,y,z)=αx+βy+γy , where $$\alpha ,\beta ,\gamma $$ α,β,γ are real numbers not all zero. We characterize all translating solitons that are foliated by circles and the ones that are graphs of type $$z=f(x)+g(y)$$ z=f(x)+g(y) .

article

The one dimensional case of the singular minimal surfaces with density

Rafael López

Geometriae Dedicata > 2019 > 200 > 1 > 303-320

Given $$\alpha ,\lambda \in \mathbb {R}$$ α , λ ∈ R , a singular minimal surface with density vector $$\mathbf {v}$$ v is a surface $$\Sigma $$ Σ in Euclidean space whose mean curvature H satisfies $$2H(p)= \alpha \langle N(p),\mathbf {v}\rangle /\langle p,\mathbf {v}\rangle +2\lambda $$ 2 H ( p ) = α ⟨ N ( p ) , v ⟩ / ⟨ p , v ⟩ + 2 λ , $$p\in \Sigma $$ ...

article

Reply to comments on: “Tethyan calpionellids in the Neuquén Basin (Argentine Andes), their significance in defining the Jurassic/Cretaceous boundary and pathways for Tethyan-Eastern Pacific connections” by Kietzmann & Iglesia Llanos

Rafael López-Martínez, Beatriz Aguirre-Urreta, Marina Lescano, Andrea Concheyro, more

Journal of South American Earth Sciences > 2018 > 84 > C > 448-453

The comments by Kietzmann & Iglesia Llanos (Comment on “Tethyan calpionellids in the Neuquén Basin (Argentine Andes), their significance in defining the Jurassic/Cretaceous boundary and pathways for Tethyan-Eastern Pacific connections” by R. López-Martínez, B. Aguirre-Urreta, M. Lescano, A. Concheyro, V. Vennari and V. Ramos) on our paper published in the Journal of South American Earth Sciences...

article

First-line ribociclib plus letrozole in postmenopausal women with HR+ , HER2− advanced breast cancer: Tumor response and pain reduction in the phase 3 MONALEESA-2 trial

Wolfgang Janni, Emilio Alba, Thomas Bachelot, Sami Diab, more

Breast Cancer Research and Treatment > 2018 > 169 > 3 > 469-479

Purpose The phase 3 MONALEESA-2 study demonstrated that addition of ribociclib (RIB) to letrozole (LET) significantly improved progression-free survival (PFS) in patients (pts) with hormone receptor-positive (HR+), HER2-negative (HER2−) advanced breast cancer (ABC). Here, we evaluated duration of response (DoR), tumor shrinkage, PFS by treatment-free interval (TFI), and health-related quality of life...

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INFONA - science communication portal

Search results for: Rafael López

Classification and Construction of Minimal Translation Surfaces in Euclidean Space

Patient preference for oral chemotherapy in the treatment of metastatic breast and lung cancer

Ultra-Small Platinum Nanoparticles with High Catalytic Selectivity Synthesized by an Eco-friendly Method Supported on Natural Hydroxyapatite

Exosome-mimetic nanoplatforms for targeted cancer drug delivery

Association of GSTP1 and ERCC1 polymorphisms with toxicity in locally advanced head and neck cancer platinum‐based chemoradiotherapy treatment

The role of clonal communication and heterogeneity in breast cancer

LESM—An object‐oriented MATLAB program for structural analysis of linear element models

Presence and Spatial Distribution of Polynuclear Aromatic Hydrocarbons (PAHs) in Groundwater of Merida City, Yucatan, Mexico

CTCs‐derived xenograft development in a triple negative breast cancer case

Surfaces with a canonical principal direction and prescribed mean curvature

Food addiction and impaired executive functions in women with obesity

Food addiction and preoperative weight loss achievement in patients seeking bariatric surgery

2018 Annual Report of the European Liver Transplant Registry (ELTR) – 50‐year evolution of liver transplantation

The Dirichlet problem for the $$\alpha $$ α -singular minimal surface equation

Efficient algorithm for expanding theoretical electron densities in canterakis–zernike functions

Compact $$\lambda $$ λ -translating Solitons with Boundary

Some geometric properties of translating solitons in Euclidean space

The one dimensional case of the singular minimal surfaces with density

Reply to comments on: “Tethyan calpionellids in the Neuquén Basin (Argentine Andes), their significance in defining the Jurassic/Cretaceous boundary and pathways for Tethyan-Eastern Pacific connections” by Kietzmann & Iglesia Llanos

First-line ribociclib plus letrozole in postmenopausal women with HR+ , HER2− advanced breast cancer: Tumor response and pain reduction in the phase 3 MONALEESA-2 trial

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