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Abstract. A 65-year-old male who had been diagnosed as having chronic lymphocytic leukemia (CLL) stage Rai0 three years previously presented in October 1998 with progressive disease (splenomegaly, increasing lymphocytosis: 30/nl) and 50% prolymphocytes in his peripheral blood. The patient was refractory to initial treatment with fludarabine and epirubicin, and 2-chlorodeoxyadenosine. Additionally,...
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