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Hypercoagulability is associated with chronic kidney disease (CKD). Tissue factor/factor VIIa complex and factor Xa in the coagulation cascade are known to activate protease–activated receptor 2 (PAR2), and to cause inflammation and tissue injury. Although PAR2 is highly expressed in the kidney, it is unclear whether PAR2 plays a pathogenic role in CKD. To test this, we fed the mice lacking Par2 (F2rl1...
The shepherding problem is to consider how a shepherd moves to herd sheep from their initial position to some target position. This problem arises in various situations in nature and has a number of useful applications such as in robotics and crowd control. Many simulations have been conducted to investigate herd and group behaviours. In contrast to these swarm analyses, fewer studies have investigated...
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