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Adrenomedullary chromaffin (AMC) cells are sensitive to hypoxia in the newborn, but whether this property is lost during postnatal maturation is a matter of controversy. We have developed a rat adrenal slice preparation that allows the study of neonatal and adult AMC cell sensitivity to hypoxia in almost optimal physiological conditions. Responses to secretagogues can be quantitatively and noninvasively...
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