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n‐Alkanes are ubiquitous in nature and serve as important carbon sources for both Gram‐positive and Gram‐negative bacteria. Hydroxylation of n‐alkanes by alkane monooxygenases is the first and most critical step in n‐alkane metabolism. However, regulation of alkane degradation genes in Gram‐positive bacteria remains poorly characterized. We therefore explored the transcriptional regulation of an alk...
Sinorhizobium meliloti DctB is a typical transmembrane sensory histidine kinase, which senses C4‐dicarboxylic acids (DCA) and regulates the expression of DctA, the DCA transporter. We previously reported the crystal structures of its periplasmic sensory domain (DctBp) in apo and succinate‐bound states, and these structures showed dramatic conformational changes at dimeric level. Here we show a ligand‐induced...
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