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Drug resistance is a major obstacle that limits the effectiveness of cancer therapy. Many cancer cells acquire resistance mechanisms that allow them to survive apoptosis, contributing to the initiation and progression of cancers. Therefore, novel therapeutic strategies are needed to address the emerging problem of drug resistance. Recent studies have suggested that the induction of autophagy could...
CCN2/CTGF is a multifunctional molecule that has been shown to play a central role in chondrocyte differentiation. During this process, the expression of ccn2 is tightly regulated to confer a maximal level at prehypertrophic – hypertrophic stages, in which the 3'-untranslated region (UTR) of the mRNA is critically involved in mediating its post-transcriptional regulation. In our previous studies,...
Energy storage system is used in power-grid to compensate for the power fluctuation caused by renewable energy systems. This paper presents loss-analysis results of power converter utilized for the energy-storage systems. The system has multiple energy storage devices such as a LaB and an EDLC. This paper discusses two methods to distribute the compensation power reference to each device. Conventional...
This paper focuses on the circuit which is to reduce the number of switching elements in comparison to a common multi-level inverter NPC inverter. Increasing the number of levels of the output voltage at reduced circuit number switching elements, and performs waveform improvement. Typically, the ratio of the input voltage of the multi-level inverter is E1 : E2 = 1 : 1. When the ratio of the input...
This paper discusses a control method for an electrolytic capacitor-less single-phase AC/DC converter with PFC capability and with constant dc-output voltage. Generally, single-phase AC/DC converters employ bulky electrolytic capacitors in order to smoothen the ripple power with twice the utility frequency. The proposed control method uses a T-type NPC circuit with a small film capacitor and decouple...
An energy storage system is integrated into a power-grid to compensate for the power fluctuation from renewable energy systems. This paper proposes a high-efficiency and low-cost energy storage system for the power-grid. The proposed system combines multi-energy storage devices such as a LaB and an EDLC for reducing the cost incurred by the system for the complete operation period. This paper also...
In the future, Automated Demand Response (ADR) Aggregators will be expected to gather power curtailments as quickly as possible. In this research, the total delay for the ADR aggregation of large-scale building HVAC facilities was evaluated by test-bench experiments. A power curtailment delay model of 100 buildings was constructed by using time-series data measured from actual office building HVAC...
The increasing demand for Renewable Energy Sources like solar and wind power opens up adoption of Web services communications for wide-area and real-time smart grid applications. Since the behavior of web services with TCP/IP is stochastic, detailed characteristics of data transmission delay should be investigated for time-constraint smart grid communications. In this paper, we have chosen a new Web...
Real-time demand control is expected for the future smart grid with intensive renewable energy sources (RESs). The Variable Refrigerant Flow (VRF) building HVAC (Heating Ventilation and Air-Conditioning) facilities are popular in modern buildings in Japan, Europe, and other countries. The VRF HVAC type uses sophisticated refrigerant flow control devices. We propose a fine-time-granularity fast demand...
Uninterruptible power supplies (UPSs) are widely used to overcome instantaneous voltage drops and complete power failures. This paper proposes a novel single-phase standby UPS with a small size and high reliability. The proposed UPS consists of a buck-boost converter and a full-bridge inverter; this device eliminates the need for bulky electrolytic capacitors or output LC-filtering. The buck-boost...
This paper proposes a method for reconstructing the three-phase voltage output of a current source inverter (CSI). The method produces a three-phase voltage by using the DC-link voltage and the switching pattern of the CSI and improves the reconstructed waveform by using the delay time of a filter. The proposed method can reduce errors between the actual voltage and the reconstructed voltage at the...
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