The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
MicroRNA‐9‐1(miR‐9‐1) plays an important role in the mechanism that regulates the lineage fate of differentiating hematopoietic cells. Recent studies have shown that miR‐9‐1 is downregulated in t (8; 21) AML. However, the pathogenic mechanisms underlying miR‐9‐1 downregulation and the RUNX1‐RUNX1T1 fusion protein, generated from the translocation of t (8; 21) in AML, remain unclear. RUNX1‐RUNX1T1...
The t(8;21)(q22;q22) translocation is the most common chromosomal translocation in acute myeloid leukemia (AML), and it gives rise to acute myeloid gene 1 (AML1)–myeloid transforming gene 8 (ETO)‐positive AML, which has a relatively favorable prognosis. However, the molecular mechanism related to a favorable prognosis in AML1–ETO‐positive AML is still not fully understood. Our results show that the...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.