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The goal of the study was to investigate the effects of focal brain cooling on epileptic discharges (EDs) and background rhythms in the sensorimotor cortex of anesthetized rats using spectral analysis of electroencephalography (EEG).Penicillin G was administered intracortically into superficial layers of the left sensorimotor cortex and EDs were induced. Focal brain cooling was achieved using a cooling...
To investigate the effect of focal brain cooling on seizure, spectral analysis of electroencephalography (EEG) was performed in anesthetized rats intracortically injected with penicillin G potassium. Penicillin G induced epileptic discharges (EDs) and increased high frequency EEG bands. Use of a cooling device suppressed EDs with an effect that depended on the brain temperature. Fast Fourier Transform...
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