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Aim
CCN family member 1 (CCN1) is an extracellular matrix cytokine and appears in atherosclerotic lesions. However, we have no evidence to support the role of CCN1 in regulating cholesterol metabolism and atherosclerosis.
Methods
Apolipoprotein E‐deficient (apoE−/−) mice were used as in vivo model. Oxidized low‐density lipoprotein (oxLDL)‐induced macrophage‐foam cells were used as in vitro model...
ScopeEpigallocatechin‐3‐gallate (EGCG), the most abundant catechin of green tea, has beneficial effects on physiological functions of endothelial cells (ECs), yet the detailed mechanisms are not fully understood. In this study, we investigated the role of transient receptor potential vanilloid type 1 (TRPV1), a ligand‐gated nonselective calcium channel, in EGCG‐mediated endothelial nitric oxide (NO)...
BK virus, a human polyomavirus, may cause nephritis and urological disorders in patients who have undergone renal transplantation. Little is known about the characteristics of the BK viral proteins. In the current study, BK viral proteins were characterized by immunoblotting and LC-MS/MS. The results revealed that BK virus is composed of three structural proteins, VP1, VP2, and VP3 and four cellular...
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