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Lewis rats were injected with recombinant murine tumour necrosis factor-α either intravitreally (0·08–50 ng) or intracardially (1 μg). The intraocular inflammatory response induced by tumour necrosis factor was examined by slit-lamp and protein extravasation into aqueous humor was determined. The phenotype of the inflammatory cells in the eye was analysed by immunohistochemistry. In addition, the...