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Recent work has suggested that the ovarian steroid hormone, 17β-estradiol (E2), at physiological concentrations, may exert protective effects in neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease and acute ischemic stroke. While physiological concentrations of E2 have consistently been shown to be protective in vivo, direct protection of neurons remains controversial, suggesting...
Since the cloning of leptin by Friedman's laboratory in 1994, over 3000 papers have been published on leptin, making it one of the most active research areas in all of science. Leptin appears to be a pleiotrophic hormone affecting many different tissues in the body. This review focuses on the role of leptin in reproduction. Evidence is accumulating that leptin potentially has roles in the regulation...
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