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Randomised phase III trials are the ideal setting for prospective collection of economic and health related quality of life (HRQL) data. Many studies combine prospective clinical data with economic assumptions or data collected in separate costing studies. To extrapolate the trial outcomes to lifelong consequences, modelling approaches are often used. Also, in situations where no randomised trial...
Purpose: The aim of this study was to calculate the costs of chemotherapy and high-dose-rate brachytherapy in advanced-stage nasopharyngeal cancer. It is argued whether the effect of chemotherapy and this type of high-dose, high-precision radiation therapy is worth the costs.Methods and Materials: Clinical results of Stage III-IVB nasopharyngeal cancer in patients treated between 1991 and 2000 are...
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