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The study is devoted to the development of a new gel system, based on a copolymer between itaconic anhydride and 3, 9-divinyl-2, 4, 8, 10-tetraoxaspiro (5.5) undecane (PITAU) and hyaluronic acid, used as a potential platform for drug delivery. PITAU is characterized by good capacity of gel network formation, and good biocompatibility, while hyaluronic acid, a polysaccharide present in the human body,...
New hydrogels based on entrapped poly(aspartic acid) (PAS) into hyaluronic acid (HA) crosslinked network were obtained to improve the sensitive characteristics, especially the pH responsiveness of the hyaluronic gels. The interactions between the macromolecular chains were sustained by rheological test, zeta potential, and hydrodynamic diameter and conductivity determinations. In situ and static evaluation...
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