Search results for: Kuiran Dong

Items from 1 to 20 out of 28 results

article

Clinical outcome of infantile‐onset inflammatory bowel disease in 102 patients with interleukin‐10 signalling deficiency

Ziqing Ye, Lai Qian, Wenhui Hu, Shijian Miao, more

Alimentary Pharmacology & Therapeutics > 55 > 11 > 1414 - 1422

Background Infantile‐onset inflammatory bowel disease can be caused by defects in interleukin‐10 signalling. The natural history and clinical outcomes of allogeneic haematopoietic stem cell transplantation, medical treatment and surgery have not been thoroughly described. Aims This study evaluates disease progression and clinical outcome in patients with interleukin‐10 signalling deficiency. ...

article

Circulating tumor DNA in neuroblastoma

Meng Wei, Mujie Ye, Kuiran Dong, Rui Dong

Pediatric Blood & Cancer > 67 > 10 > n/a - n/a

As a sympathetic nervous system–derived tumor, aggressive neuroblastoma (NB) is currently attracting interest from researchers seeking diagnostic and prognostic markers via less invasive procedures. The analysis of circulating tumor DNA (ctDNA) in peripheral blood can provide genetic information from multiple tumor lesions and is not dependent on a surgical procedure. The identification of genetic...

article

Retroperitoneal kaposiform hemangioendothelioma complicated by Kasabach‐Merritt phenomenon and obstructive jaundice: A retrospective series of 3 patients treated with sirolimus

Wei Yao, Kai Li, Zuopeng Wang, Kuiran Dong, more

Pediatric Dermatology > 37 > 4 > 677 - 680

We present a retrospective case series of 3 patients with retroperitoneal kaposiform hemangioendothelioma (KHE) complicated by Kasabach‐Merritt phenomenon (KMP) and biliary obstruction. We found sirolimus to be a safe and effective treatment for these patients who were refractory to other treatment modalities. However, our patients were slow to respond in comparison to published reports of sirolimus...

article

Sirolimus therapy for kaposiform hemangioendothelioma with long‐term follow‐up

Zuopeng Wang, Wei Yao, Hongqiang Sun, Kuiran Dong, more

The Journal of Dermatology > 46 > 11 > 956 - 961

Mammalian target of rapamycin inhibitors have shown promising results in the management of kaposiform hemangioendothelioma (KHE). The purpose of this study was to present our experience involving sirolimus therapy for KHE. A retrospective study was conducted to review the medical documents of 26 patients with KHE who were treated with sirolimus at our hospital between March 2012 and December 2016...

article

Clinical characteristics and prognosis of adrenocortical tumors in children

Zuopeng Wang, Gongbao Liu, Hongqiang Sun, Kai Li, more

Pediatric Surgery International > 2019 > 35 > 3 > 365-371

Purpose The purpose of this study was to review the clinical characteristics and prognosis of children with adrenocortical tumors (ACT). Methods We retrospectively reviewed the medical records of 28 patients with ACT at our hospital between March 2010 and March 2017. Results The main clinical presentations were sexual prematurity (n = 17) and Cushing’s syndrome (n = 15). All patients without metastasis...

article

Reoperation after Ladd’s procedure in the neonatal period

Haitao Zhu, Shan Zheng, Mashriq Alganabi, Xueni Peng, more

Pediatric Surgery International > 2019 > 35 > 1 > 117-120

Aim of the study To investigate (1) the indications for reoperation after neonatal Ladd’s procedure, (2) the type of reoperation and (3) its outcome. Methods We reviewed all neonatal Ladd’s procedures in our hospital from 2003 to 2017 and the outcomes of reoperation in these patients. Main results 252 neonates had Ladd’s procedure: 59 were laparoscopic (23.4%) and 193 open (76.6%). 15 (6.0%) required...

article

The Diagnosis Effect of DNA Methylation in Inflammatory Bowel Diseases

Baihui Liu, Kuiran Dong, Rui Dong

Gastroenterology > 2018 > 155 > 1 > 229

article

Comparison of long-term prognosis of laparoscopic and open adrenalectomy for local adrenal neuroblastoma in children

Wei Yao, Kuiran Dong, Kai Li, Shan Zheng, more

Pediatric Surgery International > 2018 > 34 > 8 > 851-856

Objective To investigate and compare long-term outcomes in children undergoing laparoscopic or open adrenalectomy for local adrenal neuroblastoma. Methods A retrospective review was conducted of 37 children with local adrenal neuroblastoma treated between January 2005 and December 2013 in our hospital. These patients met inclusion criteria for having adrenal neuroblastoma and undergoing operative...

article

Separation of pygopagus, omphalopagus, and ischiopagus with the aid of three-dimensional models

Xiangqi Liu, Kuiran Dong, Shan Zheng, Xianmin Xiao, more

Journal of Pediatric Surgery > 2018 > 53 > 4 > 682-687

The three-dimensional (3D) technique provides with accurate anatomical information. We present the separation surgeries for three different kinds of conjoined twins with the aid of three-dimensional techniques.For the pygopagus twins, a pelvic and lower vertebral model was made. For the omphalopagus and ischiopagus, their enhanced computed tomography (CT) scan images were transferred to the Computer-Assisted...

article

Clinical and pathological features of patients with biliary atresia who survived for more than 5 years with native liver

Song Sun, Shan Zheng, Xuexin Lu, Gong Chen, more

Pediatric Surgery International > 2018 > 34 > 4 > 381-386

Purpose The objective of this study was to determine the predictive index for prognosis in patients with biliary atresia (BA). Methods A total of 71 patients were divided into two groups. Group A included 39 postoperative BA patients who survived for more than 5 years with normal liver function and did not present cirrhosis, and group B included 32 patients who died from liver failure within 1 year...

article

Usefulness of posterior sagittal anorectoplasty for redo pull-through in complicated and recurrent Hirschsprung disease: Experience with a single surgical group

Song Sun, Gong Chen, Shan Zheng, Kuiran Dong, more

Journal of Pediatric Surgery > 2017 > 52 > 3 > 458-462

To retrospectively examine 12 patients with Hirschsprung disease (HD) who underwent posterior sagittal anorectoplasty (PSARP) for various complications.This study included patients with HD who underwent redo pull-through (PT) via PSARP at our institute between 2005 and 2014. The type of initial procedure, clinical presentations, indications, and functional results were analyzed. Postoperative excretory...

article

Downregulation of bone morphogenetic protein receptor 2 promotes the development of neuroblastoma

Ximao Cui, Yili Yang, Deshui Jia, Ying Jing, more

Biochemical and Biophysical Research Communications > 2017 > 483 > 1 > 609-616

Neuroblastoma (NB) is the most common extracranial solid tumor of childhood. In this study, we examined the expression of bone morphogenetic protein receptor 2 (BMPR2) in primary NB and adjacent non-tumor samples (adrenal gland). BMPR2 expression was significantly downregulated in NB tissues, particularly in high-grade NB, and was inversely related to the expression of the NB differentiation markers...

article

Analysis of clinical features and outcomes for inflammatory myofibroblastic tumors in China: 11 years of experience at a single center

Zuopeng Wang, Xiaolong Zhao, Kai Li, Wei Yao, more

Pediatric Surgery International > 2016 > 32 > 3 > 239-243

Purpose Inflammatory myofibroblastic tumor (IMT) is a rare benign neoplasm. The purpose of this study was to review the clinical characteristics, imaging and pathological features, and outcomes of children with IMTs from a single center in China. Methods A retrospective file review was conducted involving 23 cases of pathologically confirmed IMTs treated at the Children’s Hospital between April...

article

Reoperation for anastomotic complications of esophageal atresia and tracheoesophageal fistula

Haitao Zhu, Chun Shen, Xianmin Xiao, Kuiran Dong, more

Journal of Pediatric Surgery > 2015 > 50 > 12 > 2012-2015

The purpose of the study was to review our experience in the re-operative management of anastomotic complications (ACs) following primary repair of esophageal atresia (EA) and tracheoesophageal fistula (TEF) and to assess the outcomes after reoperation.We retrospectively reviewed 21 EA patients who underwent reoperation from 2005 to 2014. Clinical features, reasons for reoperation, diagnosis of ACs,...

article

Treatment of retroperitoneal kaposiform hemangioendothelioma: 2 case reports

Kai Li, Xianmin Xiao, Kuiran Dong, Wei Yao, more

Journal of Pediatric Surgery Case Reports > 2015 > 3 > 7 > 276-279

•Retroperitoneal kaposiform hemangioendothelioma (R-KHE) is a kind of rare vascular tumor.•The definitive diagnosis is difficult and often confused with retroperitoneal tumor, hematologic tumor or hemorrhagic enteritis.•The clinical characteristics are early onset in 2–4 months old babies and low platelets.•Careful observation, comprehensive judgment, bold hypothesis, multidisciplinary consultation...

article

Successful treatment of kaposiform lymphangiomatosis with sirolimus

Zuopeng Wang, Kai Li, Wei Yao, Kuiran Dong, more

Pediatric Blood & Cancer > 62 > 7 > 1291 - 1293

Generalized lymphatic anomaly (GLA) is a rare and often fatal congenital lymphatic disorder that also commonly affects bone. Kaposiform lymphangiomatosis (KLA) is a novel subtype of GLA with poor prognosis and no proper treatment guidelines. A 9‐year‐old male with recurrent pleural effusion was clinically diagnosed as KLA. Following sirolimus therapy at a dose of 0.8 mg/m² twice daily, pleural effusion...

article

Refractory Kasabach–Merritt phenomenon successfully treated with sirolimus, and a mini‐review of the published work

Zuopeng Wang, Kai Li, Kuiran Dong, Xianmin Xiao, more

The Journal of Dermatology > 42 > 4 > 401 - 404

Kasabach–Merritt phenomenon (KMP) is a rare and life‐threatening disease involving a vascular tumor combined with severe consumptive coagulopathy. We present for the first time a case of KMP with the vascular tumor involving two anatomical sites; the patient failed to respond to steroids and vincristine. Following sirolimus therapy at a dose of 0.8 mg/m² twice daily, the lesions shrank and the platelet...

article

Steroid‐resistant kaposiform hemangioendothelioma: A retrospective study of 37 patients treated with vincristine and long‐term follow‐up

Zuopeng Wang, Kai Li, Wei Yao, Kuiran Dong, more

Pediatric Blood & Cancer > 62 > 4 > 577 - 580

BackgroundKaposiform hemangioendothelioma (KHE) with Kasabach–Merritt phenomenon (KMP) still remains a particular and life‐threatening disease. The purpose of this study was to evaluate the efficacy of vincristine (VCR) and the possibility of replacement with steroids in the treatment of steroid‐resistant KHE with KMP. ProcedureWe retrospectively reviewed the medical records of 37 patients with steroid‐resistant...

article

TERT promoter mutation during development of hepatoblastoma to hepatocellular carcinoma

Rui Dong, Shan Zheng, Kuiran Dong

Journal of Hepatology > 2015 > 62 > 2 > 497

article

Analysis of recurrence risks for sacrococcygeal teratoma in children

Wei Yao, Kai Li, Shan Zheng, Kuiran Dong, more

Journal of Pediatric Surgery > 2014 > 49 > 12 > 1839-1842

The purpose of this study was to investigate effects of risk factors on recurrence of sacrococcygeal teratoma (SCT).A retrospective review was conducted of 107 SCTs treated between January 2003 and December 2012 in our center. Risk factors were identified by univariate and multivariate analysis.Sixteen children had recurrence of SCT a median interval of 16.25months after primary surgery. 15.6% tumors...

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INFONA - science communication portal

Search results for: Kuiran Dong

Clinical outcome of infantile‐onset inflammatory bowel disease in 102 patients with interleukin‐10 signalling deficiency

Circulating tumor DNA in neuroblastoma

Retroperitoneal kaposiform hemangioendothelioma complicated by Kasabach‐Merritt phenomenon and obstructive jaundice: A retrospective series of 3 patients treated with sirolimus

Sirolimus therapy for kaposiform hemangioendothelioma with long‐term follow‐up

Clinical characteristics and prognosis of adrenocortical tumors in children

Reoperation after Ladd’s procedure in the neonatal period

The Diagnosis Effect of DNA Methylation in Inflammatory Bowel Diseases

Comparison of long-term prognosis of laparoscopic and open adrenalectomy for local adrenal neuroblastoma in children

Separation of pygopagus, omphalopagus, and ischiopagus with the aid of three-dimensional models

Clinical and pathological features of patients with biliary atresia who survived for more than 5 years with native liver

Usefulness of posterior sagittal anorectoplasty for redo pull-through in complicated and recurrent Hirschsprung disease: Experience with a single surgical group

Downregulation of bone morphogenetic protein receptor 2 promotes the development of neuroblastoma

Analysis of clinical features and outcomes for inflammatory myofibroblastic tumors in China: 11 years of experience at a single center

Reoperation for anastomotic complications of esophageal atresia and tracheoesophageal fistula

Treatment of retroperitoneal kaposiform hemangioendothelioma: 2 case reports

Successful treatment of kaposiform lymphangiomatosis with sirolimus

Refractory Kasabach–Merritt phenomenon successfully treated with sirolimus, and a mini‐review of the published work

Steroid‐resistant kaposiform hemangioendothelioma: A retrospective study of 37 patients treated with vincristine and long‐term follow‐up

TERT promoter mutation during development of hepatoblastoma to hepatocellular carcinoma

Analysis of recurrence risks for sacrococcygeal teratoma in children

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