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Intravascular superparamagnetic iron oxide nanoparticles (SPION)-enhanced MR transverse relaxation rates (∆R2⁎ and ∆R2) are widely used to investigate in vivo vascular parameters, such as the cerebral blood volume (CBV), microvascular volume (MVV), and mean vessel size index (mVSI, ∆R2⁎/∆R2). Although highly efficient, regional comparison of vascular parameters acquired using gradient-echo based ∆R...
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