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Anin vitro cultured rat perirenal preadipocyte (PA) was established as a model system to investigate the role of the intracellular pH (pHi) and of the Na+ /H+ exchanger during PA proliferation and differentiation. pH sensitive probe, 2′,7′-bis-(2-carboxyethyl)-5(6)-carboxyfluorescein(BCECF), was employed to measure the pHi of PA and to determine the Na+/H+ exchange activity. The results showed that...
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