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The transcription factor Foxp3 plays a key role in CD4 + CD25 + regulatory T (Treg) cell function. A correlation has been shown between survival and the frequency of tumor-infiltrating Foxp3-positive Treg cells in cancer patients. However, few studies have characterized the regulation of Foxp3 expression and function in Treg cells, which are known to comprise distinct subsets, with...
The aqueous extract of the tuber of Smilax china L., popularly known in China as “Jin Gang Ten”, was tested for its anti-inflammatory activities in rats by egg-albumin-induced edema and anti-nociceptive effects in mice using hot-plate test and acetic acid-induced abdominal constriction test, respectively. The aqueous extract in the dose of 1000mg/kg (i.g.) had a significant anti-nociceptive and anti-inflammatory...
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