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This series of experiments examined whether epinephrine (EPI) produces the same thermoregulatory effects in the cold that have been reported for norepinephrine and isoproterenol. Lean and obese Zucker rats were trained to press a lever to activate infrared heat lamps in a cold (- 8°C) environment. Operant thermoregulatory behavior increased dose-dependently following EPI (0-100 μg/kg), but posttest...