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Type 1 diabetic patients require adjustments of their basal therapy due to insulin requirement changes. A very promising automatic approach is based on the so-called Run-to-Run (R2R) strategy, which adjusts the insulin therapy based on the performance measured during the previous run, usually of 1 day. Previous R2R approaches were based on a few blood glucose measurements. In this paper, the use of...
Meal compensation in blood glucose control of people affected by type 1 Diabetes is an open challenge. The proposed Model Predictive Controller (MPC) is equipped with an asymmetric quadratic cost function, postprandial (pp) input integral and pp output soft constraints. The controller is synthesized with a linear glucose-insulin model customized on the basis of the patient clinical knowledge. An in-silico...
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