Search results for: Ettore Beghi

Items from 1 to 20 out of 165 results

article

Impact of 2021 European Academy of Neurology/Peripheral Nerve Society diagnostic criteria on diagnosis and therapy of chronic inflammatory demyelinating polyradiculoneuropathy variants

Alberto De Lorenzo, Giuseppe Liberatore, Pietro Emiliano Doneddu, Fiore Manganelli, more

European Journal of Neurology > 31 > 4 > n/a - n/a

Background and purpose There are different criteria for the diagnosis of different variants of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). The 2021 European Academy of Neurology/Peripheral Nerve Society (EAN/PNS) guidelines provide specific clinical criteria for each CIDP variant even if their therapeutical impact has not been investigated. Methods We applied the clinical...

article

Management of epilepsy in older adults: A critical review by the ILAE Task Force on Epilepsy in the elderly

Loretta Piccenna, Rebecca O'Dwyer, Ilo Leppik, Ettore Beghi, more

Epilepsia > 64 > 3 > 567 - 585

Older adults represent a highly heterogeneous population, with multiple diverse subgroups. Therefore, an individualized approach to treatment is essential to meet the needs of each unique subgroup. Most comparative studies focusing on treatment of epilepsy in older adults have found that levetiracetam has the best chance of long‐term seizure freedom. However, there is a lack of studies investigating...

article

The epidemiology of epilepsy in older adults: A narrative review by the ILAE Task Force on Epilepsy in the Elderly

Ettore Beghi, Giorgia Giussani, Cinzia Costa, Jacopo C. DiFrancesco, more

Epilepsia > 64 > 3 > 586 - 601

In an aging world, it is important to know the burden of epilepsy affecting populations of older persons. We performed a selective review of epidemiological studies that we considered to be most informative, trying to include data from all parts of the world. We emphasized primary reports rather than review articles. We reviewed studies reporting the incidence and prevalence of epilepsy that focused...

article

Comparative features and outcomes of major neurological complications of COVID‐19

Ettore Beghi, Elena Moro, Eugenia Irene Davidescu, Bogdan Ovidiu Popescu, more

European Journal of Neurology > 30 > 2 > 413 - 433

Background and purpose The aim of this study was to assess the neurological complications of SARS‐CoV‐2 infection and compare phenotypes and outcomes in infected patients with and without selected neurological manifestations. Methods The data source was a registry established by the European Academy of Neurology during the first wave of the COVID‐19 pandemic. Neurologists collected data on patients...

article

Effect of RNS60 in amyotrophic lateral sclerosis: a phase II multicentre, randomized, double‐blind, placebo‐controlled trial

Ettore Beghi, Elisabetta Pupillo, Elisa Bianchi, Valentina Bonetto, more

European Journal of Neurology > 30 > 1 > 69 - 86

Background and purpose Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with limited treatment options. RNS60 is an immunomodulatory and neuroprotective investigational product that has shown efficacy in animal models of ALS and other neurodegenerative diseases. Its administration has been safe and well tolerated in ALS subjects in previous early phase trials. Methods This...

article

International consensus recommendations for management of new onset refractory status epilepticus including febrile infection‐related epilepsy syndrome: Statements and supporting evidence

Ronny Wickstrom, Olga Taraschenko, Robertino Dilena, Eric T. Payne, more

Epilepsia > 63 > 11 > 2840 - 2864

Objective This study was undertaken to develop consensus‐based recommendations for the management of adult and pediatric patients with new onset refractory status epilepticus (NORSE)/febrile infection‐related epilepsy syndrome (FIRES) based on best evidence and experience. Methods The Delphi methodology was followed. A facilitator group of nine experts was established, who defined the scope, users,...

article

International consensus recommendations for management of new onset refractory status epilepticus (NORSE) including febrile infection‐related epilepsy syndrome (FIRES): Summary and clinical tools

Ronny Wickström, Olga Taraschenko, Robertino Dilena, Eric T. Payne, more

Epilepsia > 63 > 11 > 2827 - 2839

Objective To develop consensus‐based recommendations for the management of adult and pediatric patients with new‐onset refractory status epilepticus (NORSE)/febrile infection‐related epilepsy syndrome (FIRES) based on best available evidence and expert opinion. Methods The Delphi methodology was followed. A facilitator group of nine experts was established who defined the scope, users, and suggestions...

article

Guillain‐Barré syndrome and COVID‐19: A 1‐year observational multicenter study

Massimiliano Filosto, Stefano Cotti Piccinelli, Stefano Gazzina, Camillo Foresti, more

European Journal of Neurology > 29 > 11 > 3358 - 3367

Background and purpose Many single cases and small series of Guillain–Barré syndrome (GBS) associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection were reported during the coronavirus disease 19 (COVID‐19) outbreak worldwide. However, the debate regarding the possible role of infection in causing GBS is still ongoing. This multicenter study aimed to evaluate epidemiological...

article

COVID‐19 vaccination hesitancy among people with chronic neurological disorders: A position paper

Martin Rakusa, Serefnur Öztürk, Elena Moro, Raimund Helbok, more

European Journal of Neurology > 29 > 8 > 2163 - 2172

Background and purpose Health risks associated with SARS‐CoV‐2 infection are undisputed. Moreover, the capability of vaccination to prevent symptomatic, severe, and fatal COVID‐19 is recognized. There is also early evidence that vaccination can reduce the chance for long COVID‐19. Nonetheless, the willingness to get vaccinated and receive booster shots remains subpar among people with neurologic...

article

Neurological Events Reported after COVID‐19 Vaccines: An Analysis of Vaccine Adverse Event Reporting System

Jennifer A. Frontera, Arina A. Tamborska, Mohamed F. Doheim, David Garcia‐Azorin, more

Annals of Neurology > 91 > 6 > 756 - 771

Objective To identify the rates of neurological events following administration of mRNA (Pfizer, Moderna) or adenovirus vector (Janssen) vaccines in the U.S. Methods We used publicly available data from the U.S. Vaccine Adverse Event Reporting System (VAERS) collected between January 1, 2021 and June 14, 2021. All free text symptoms that were reported within 42 days of vaccine administration were...

article

Short‐ and long‐term outcome and predictors in an international cohort of patients with neuro‐COVID‐19

Ettore Beghi, Raimund Helbok, Serefnur Ozturk, Omer Karadas, more

European Journal of Neurology > 29 > 6 > 1663 - 1684

Background and purpose Despite the increasing number of reports on the spectrum of neurological manifestations of COVID‐19 (neuro‐COVID), few studies have assessed short‐ and long‐term outcome of the disease. Methods This is a cohort study enrolling adult patients with neuro‐COVID seen in neurological consultation. Data were collected prospectively or retrospectively in the European Academy of...

article

The global cost of epilepsy: A systematic review and extrapolation

Charles Begley, Ryan G. Wagner, Annette Abraham, Ettore Beghi, more

Epilepsia > 63 > 4 > 892 - 903

Objective Global action for epilepsy requires information on the cost of epilepsy, which is currently unknown for most countries and regions of the world. To address this knowledge gap, the International League Against Epilepsy Commission on Epidemiology formed the Global Cost of Epilepsy Task Force. Methods We completed a systematic search of the epilepsy cost‐of‐illness literature and identified...

article

Survey on the worldwide availability and affordability of antiseizure medications: Report of the ILAE Task Force on Access to Treatment

Virginia Pironi, Ornella Ciccone, Ettore Beghi, Hazel Paragua‐Zuellig, more

Epilepsia > 63 > 2 > 335 - 351

Health systems worldwide are challenged in the provision of basic medical services and access to treatments for chronic conditions. Epilepsy, the most common severe chronic neurological disorder, does not receive sufficient attention despite being officially declared a public health priority by the World Health Organization. More than 80% of people with epilepsy live in middle‐ and low‐income countries...

article

Lessons learned from people with neurological diseases at the time of COVID‐19: The EFNA‐EAN survey

Benedetta Bodini, Elena Moro, Joke Jaarsma, Elizabeth Cunningham, more

European Journal of Neurology > 29 > 1 > 318 - 323

Background and purpose The European Federation of Neurological Associations (EFNA), in partnership with the NeuroCOVID‐19 taskforce of the European Academy of Neurology (EAN), has investigated the impact of the first wave of the COVID‐19 pandemic on individuals with neurological diseases, as well as the hopes and fears of these patients about the post‐pandemic phase. Methods An EFNA‐EAN survey...

article

A plea for equitable global access to COVID‐19 diagnostics, vaccination and therapy: The NeuroCOVID‐19 Task Force of the European Academy of Neurology

Johann Sellner, Thomas M. Jenkins, Tim J. Oertzen, Claudio L. Bassetti, more

European Journal of Neurology > 28 > 11 > 3849 - 3855

Coronavirus disease 2019 (COVID‐19), a multi‐organ disease caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), continues to challenge health and care systems around the globe. The pandemic has disrupted acute neurology services and routine patient care and has impacted the clinical course in patients with chronic neurological disease. COVID‐19 appears to have exposed inequalities...

article

Comorbidities in patients with epilepsy: Frequency, mechanisms and effects on long‐term outcome

Giorgia Giussani, Elisa Bianchi, Simone Beretta, Davide Carone, more

Epilepsia > 62 > 10 > 2395 - 2404

Objective To assess frequency, types, and mechanisms of comorbidities in people with epilepsy and verify their association with disease features and outcome. Methods This cohort study was performed in 13 Italian epilepsy centers with nationwide distribution and accurate records. Eligible patients were children and adults diagnosed before December 31, 2005, and followed for a minimum of 10 years...

article

Primary prevention of COVID‐19: Advocacy for vaccination from a neurological perspective

Johann Sellner, Thomas M. Jenkins, Tim J. von Oertzen, Claudio L. Bassetti, more

European Journal of Neurology > 28 > 10 > 3226 - 3229

article

The European Academy of Neurology COVID‐19 registry (ENERGY): an international instrument for surveillance of neurological complications in patients with COVID‐19

Ettore Beghi, Raimund Helbok, Michael Crean, Sherry Hsiang‐Yi Chou, more

European Journal of Neurology > 28 > 10 > 3303 - 3323

The COVID‐19 pandemic is a global public health issue. Neurological complications have been reported in up to one‐third of affected cases, but their distribution varies significantly in terms of prevalence, incidence and phenotypical characteristics. Variability can be mostly explained by the differing sources of cases (hospital vs. community‐based), the accuracy of the diagnostic approach and the...

article

European Academy of Neurology and European Federation of Neurorehabilitation Societies guideline on pharmacological support in early motor rehabilitation after acute ischaemic stroke

Ettore Beghi, Heinrich Binder, Codruta Birle, Natan Bornstein, more

European Journal of Neurology > 28 > 9 > 2831 - 2845

Background and purpose Early pharmacological support for post‐stroke neurorehabilitation has seen an abundance of mixed results from clinical trials, leaving practitioners at a loss regarding the best options to improve patient outcomes. The objective of this evidence‐based guideline is to support clinical decision‐making of healthcare professionals involved in the recovery of stroke survivors. ...

article

Approaches to Understanding COVID‐19 and its Neurological Associations

Ettore Beghi, Benedict D. Michael, Tom Solomon, Erica Westenberg, more

Annals of Neurology > 89 > 6 > 1059 - 1067

There is an accumulating volume of research into neurological manifestations of coronavirus disease 2019 (COVID‐19). However, inconsistent study designs, inadequate controls, poorly validated tests, and differing settings, interventions, and cultural norms weaken study quality and comparability, hence the understanding of the spectrum, burden, and pathophysiology of these complications. Therefore,...

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INFONA - science communication portal

Search results for: Ettore Beghi

Impact of 2021 European Academy of Neurology/Peripheral Nerve Society diagnostic criteria on diagnosis and therapy of chronic inflammatory demyelinating polyradiculoneuropathy variants

Management of epilepsy in older adults: A critical review by the ILAE Task Force on Epilepsy in the elderly

The epidemiology of epilepsy in older adults: A narrative review by the ILAE Task Force on Epilepsy in the Elderly

Comparative features and outcomes of major neurological complications of COVID‐19

Effect of RNS60 in amyotrophic lateral sclerosis: a phase II multicentre, randomized, double‐blind, placebo‐controlled trial

International consensus recommendations for management of new onset refractory status epilepticus including febrile infection‐related epilepsy syndrome: Statements and supporting evidence

International consensus recommendations for management of new onset refractory status epilepticus (NORSE) including febrile infection‐related epilepsy syndrome (FIRES): Summary and clinical tools

Guillain‐Barré syndrome and COVID‐19: A 1‐year observational multicenter study

COVID‐19 vaccination hesitancy among people with chronic neurological disorders: A position paper

Neurological Events Reported after COVID‐19 Vaccines: An Analysis of Vaccine Adverse Event Reporting System

Short‐ and long‐term outcome and predictors in an international cohort of patients with neuro‐COVID‐19

The global cost of epilepsy: A systematic review and extrapolation

Survey on the worldwide availability and affordability of antiseizure medications: Report of the ILAE Task Force on Access to Treatment

Lessons learned from people with neurological diseases at the time of COVID‐19: The EFNA‐EAN survey

A plea for equitable global access to COVID‐19 diagnostics, vaccination and therapy: The NeuroCOVID‐19 Task Force of the European Academy of Neurology

Comorbidities in patients with epilepsy: Frequency, mechanisms and effects on long‐term outcome

Primary prevention of COVID‐19: Advocacy for vaccination from a neurological perspective

The European Academy of Neurology COVID‐19 registry (ENERGY): an international instrument for surveillance of neurological complications in patients with COVID‐19

European Academy of Neurology and European Federation of Neurorehabilitation Societies guideline on pharmacological support in early motor rehabilitation after acute ischaemic stroke

Approaches to Understanding COVID‐19 and its Neurological Associations

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