Search results for: FU Gui

Items from 1 to 20 out of 86 results

article

Targeting RIPK3 oligomerization blocks necroptosis without inducing apoptosis

Wenjuan Li, Hengxiao Ni, Shaofeng Wu, Shang Han, more

Receptor‐interacting serine/threonine‐protein kinase 3 (RIPK3) is a central protein in necroptosis with great potential as a target for treating necroptosis‐associated diseases, such as Crohn's disease. However, blockade of RIPK3 kinase activity leads to unexpected RIPK3‐initiated apoptosis. Herein, we found that PP2, a known SRC inhibitor, inhibits TNF‐α‐induced necroptosis without initiating apoptosis...

article

A non‐covalent inhibitor XMU‐MP‐3 overrides ibrutinib‐resistant Btk^C481S mutation in B‐cell malignancies

Fu Gui, Jie Jiang, Zhixiang He, Li Li, more

British Journal of Pharmacology > 176 > 23 > 4491 - 4509

Background and Purpose Bruton's tyrosine kinase (BTK) plays a key role in B‐cell receptor signalling by regulating cell proliferation and survival in various B‐cell malignancies. Covalent low‐MW BTK kinase inhibitors have shown impressive clinical efficacy in B‐cell malignancies. However, the mutant Btk^C481S poses a major challenge in the management of B‐cell malignancies by disrupting the formation...

article

Lattice-equivalence of convex spaces

Chong Shen, Shao-Jun Yang, Dongsheng Zhao, Fu-Gui Shi

Algebra universalis > 2019 > 80 > 3 > 1-19

The links between order and topology have been extensively studied. The objective of this paper is to study the similar links between convex spaces and order structures via the lattices of convex sets. In particular, we prove a characterization of convex spaces uniquely determined by means of their lattices of convex sets, they are precisely sober and $$S_D$$ SD . One adjunction between the category...

article

Effects of forage source and particle size on chewing activity, ruminal pH, and saliva secretion in lactating Holstein cows

Fu‐Gui Jiang, Xue‐Yan Lin, Zhen‐Gui Yan, Zhi‐Yong Hu, more

Animal Science Journal > 90 > 3 > 382 - 392

The present study investigated the effects of dietary forage source (quality) and particle size on chewing activity, saliva secretion, and ruminal pH. Twelve multiparous lactating Holstein cows, four of which were ruminally cannulated, were used in a replicated 4 × 4 Latin square experimental design with a 2 × 2 factorial arrangement of treatments. Cows fed wild‐rye hay diets had longer daily eating...

article

Nomogram for predicting preoperative lymph node involvement in patients with invasive micropapillary carcinoma of breast: a SEER population-based study

Fu-Gui Ye, Chen Xia, Ding Ma, Pei-Yang Lin, more

BMC Cancer > 2018 > 18 > 1 > 1-9

Background Invasive micropapillary carcinoma (IMPC) is an unusual and distinct subtype of invasive breast tumor with high propensity for regional lymph node metastases. This study was to identify risk factors accounting for IMPC of the breast and to develop a nomogram to preoperatively predict the probability of lymph node involvement. Methods A retrospective review of the clinical and pathology...

article

Construction of tissue‐engineered lymphatic vessel using human adipose derived stem cells differentiated lymphatic endothelial like cells and decellularized arterial scaffold: A preliminary study

Yi Yang, Jian‐Tao Yang, Xiao‐Hu Chen, Ben‐Gang Qin, more

Biotechnology and Applied Biochemistry > 65 > 3 > 428 - 434

We have previously demonstrated that human adipose‐derived stem cells (hADSCs) can be differentiated into lymphatic endothelial like cells. The purpose of this study was to investigate the feasibility of utilizing the induced lymphatic endothelial like cells and decellularized arterial scaffold to construct the tissue‐engineered lymphatic vessel. The hADSCs were isolated from adipose tissue in healthy...

article

An extended data envelopment analysis for the decision-making

Xiao-Li Meng, Fu-Gui Shi

Journal of Inequalities and Applications > 2017 > 2017 > 1 > 1-16

Based on the CCR model, we propose an extended data envelopment analysis to evaluate the efficiency of decision making units with historical input and output data. The contributions of the work are threefold. First, the input and output data of the evaluated decision making unit are variable over time, and time series method is used to analyze and predict the data. Second, there are many sample decision...

article

Gill remodeling in response to hypoxia and temperature occurs in the hypoxia sensitive blunt snout bream (Megalobrama amblycephala)

Cheng-Bin Wu, Zi-Yin Liu, Fu-Gui Li, Jie Chen, more

Aquaculture > 2017 > 479 > C > 479-486

In this study, we found that blunt snout bream (Megalobrama amblycephala) had a relatively high critical oxygen tension at which it lost its equilibrium (LOE_crit), confirming that it is a hypoxia sensitive fish. Blunt snout bream has the ability to remodel its gill structure in response to oxygen levels. When blunt snout bream were exposed to 4- or 7-days of hypoxia, the average protruding lamella...

article

An extended inequality approach for evaluating decision making units with a single output

Xiao-Li Meng, Fu-Gui Shi

Journal of Inequalities and Applications > 2017 > 2017 > 1 > 1-10

In this work, an extended evaluation approach for decision making units (DMUs) with a single output is proposed. Firstly, the input and output data for each DMU are changed in the same proportion until all the outputs are equal, and then the coordinate system is established with input i as the ith coordinate axis. Secondly, in the coordinate system, the production possibility set, which is spanned...

article

Subcategories of the category of L-convex spaces

Bin Pang, Fu-Gui Shi

Fuzzy Sets and Systems > 2017 > 313 > C > 61-74

In this paper, several types of L-convex spaces are introduced, including stratified L-convex spaces, convex-generated L-convex spaces, weakly induced L-convex spaces and induced L-convex spaces. Their relations are discussed category-theoretically. Firstly, it is shown that there is a Galois correspondence between the category SL-CS of stratified L-convex spaces (resp. the category WIL-CS of weakly...

article

Enhancement of R6G fluorescence by N-type porous silicon deposited with gold nanoparticles

Jia-qing Mo, Jing Jiang, Zhen-gang Zhai, Fu-gui Shi, more

Optoelectronics Letters > 2017 > 13 > 1 > 10-12

By the electrochemical anodization method, we achieve the single-layer macroporous silicon on the N-type silicon, and prepare gold nanoparticles with sodium citrate reduction method. Through injecting the gold nanoparticles into the porous silicon by immersion, the fluorescence quenching mechanism of porous silicon influenced by gold nanoparticles is analyzed. Then the macroporous silicon deposited...

article

MiR‐21 inhibitor suppressed the progression of retinoblastoma via the modulation of PTEN/PI3K/AKT pathway

Fu Gui, Zhengdong Hong, Zhipeng You, Hongxi Wu, more

Cell Biology International > 40 > 12 > 1294 - 1302

MicroRNA‐21 (miR‐21) was reported to act as an oncogene during the development of many human tumors. However, little was revealed about the function of miR‐21 in retinoblastoma (RB). In this study, we examined the expression of miR‐21 in RB tissues and explored the relationship between miR‐21 and phosphatase and tensin homolog (PTEN)/phosphatidylinositol‐3‐OH kinase (PI3K)/AKT signal. Quantitative...

article

Two New Ring A‐Cleaved Lanostane‐Type Triterpenoids and Four Known Steroids Isolated from Endophytic Fungus Glomerella sp. F00244

Kai Guo, Huiqin Fang, Fu Gui, Yuezhou Wang, more

Helvetica Chimica Acta > 99 > 8 > 601 - 607

Two new ring A‐cleaved lanostane‐type triterpenoids, glometenoid A (1) and glometenoid B (2), together with four known steroids, (20S,22E,24R)‐ergosta‐7,22‐dien‐3β,5α,6β‐triol (3), (3β,5α,8α,22E)‐ergosta‐6,22‐diene‐3,5,8‐triol (4), 5α,8α‐epidioxy‐22E‐ergosta‐6,22‐dien‐3β‐ol (5), and ergosterol (6), were isolated from the endophytic fungus Glomerella sp. F00244. Their structures were elucidated by...

chapter

Noncontanct detection of static humans using dual-channel SFCW bioradar

Fu-Lai Liang, Zhuo-Ran Zhang, Qiang An, Fu-Gui Qi, more

2016 Progress in Electromagnetic Research Symposium (PIERS) > 4302 - 4305

2016 Progress in Electromagnetic Research Symposium (PIERS)

Bioradar is an emerging concept to aim at human targets detection. Since the vital signs are weak, surrounding environment has greater interference on it. It is difficult to obtain the high performance of static human body detection and localization. Dual-channel SFCW radar is used to improve this problem and a new method of static human body detection based on dual-channel SFCW radar is proposed...

article

A combined external delivery optimization model for wind power and thermal power considering carbon trading and tradable green certificates based on Credibility theory

Li-wei Ju, Huan-huan Li, Xiaobao Yu, Fu-gui Dong, more

International Journal of Electrical Power & Energy Systems > 2016 > 78 > C > 51-60

To reduce the impact of wind power prediction error on power system operation, Credibility theory and Fuzzy chance constrained programming method are introduced while solving wind power inter-regional scheduling optimization problems. Firstly, the paper introduces the carbon trading (CT) and Tradable Green Certificates (TGC). Then, an energy independent external delivery model is constructed, which...

article

On fuzzy soft intra-regular Abel–Grassmann’s groupoids

Asad Ali, Madad Khan, Fu-Gui Shi

Afrika Matematika > 2017 > 28 > 1-2 > 171-187

In this paper, we introduce and use the concept of $$(\in _{\gamma },\in _{\gamma }\vee q_{\delta })$$ ( ∈ γ , ∈ γ ∨ q δ ) -fuzzy soft right ideals, to study the structural properties of an $$\mathcal {AG}$$ AG -groupoid. We characterize an intra-regular $$\mathcal {AG}$$ AG -groupoids using the properties of $$(\in _{\gamma },\in _{\gamma }\vee q_{\delta })$$ ...

chapter

Path Queries on Massive Graphs Based on Multi-granular Graph Partitioning

Fu-gui He, Yan-ping Zhang, Jie Chen, Ling Zhang

Lecture Notes in Computer Science > Rough Sets and Knowledge Technology > Special Session: Quotient Space Theory > 569-578

The quotient space theory can represent the world at different granularities and deal with complicated problems hierarchically. In this paper, we introduce a method for finding shortest path on massive graphs based on multi-granular graph partitioning. Path queries into two parts: preprocessing and query step. In preprocessing, we introduce a heuristic local community structure discovery algorithm...

article

Study of the Craftwork Inpilot Scale Reactor of Hydrogen Generation from Kitchen Waste

Fu Gui, Wang Zhen, Xiong Shi, Gangzhen Jiao

Procedia Environmental Sciences > 2016 > 31 > C > 497-504

Kitchen waste disposal was laid more and more importance since its using as forage was forbidden. On the other hand, as one kind of reproducible, clean and efficient resource, H2 biological producing attracted much interesting these years. This paper focus on influences of substrate refreshing manners on the hydrogen generation in SARD with mixed substrate kitchen waste and sludge, in which kitchen...

article

Functional conservation and divergence of duplicated fibroblast growth factor receptor 1 (fgfr1) genes in blunt snout bream (Megalobrama amblycephala)

Qian-Qian Zhang, Fu-Gui Li, Bo Qin, Jie Chen, more

Gene > 2015 > 573 > 2 > 225-232

Fgfr1 is a fibroblast growth factor receptor involved in regulating cell growth, proliferation, differentiation and migration. Here, we report the isolation and characterization of duplicated fgfr1 genes in blunt snout bream (Megalobrama amblycephala). Blunt snout bream fgfr1a and -1b cDNAs were found to share a relatively high sequence identity of 82%. During embryogenesis, both fgfr1a and -1b mRNAs...

article

Two follistatin-like 1 homologs are differentially expressed in adult tissues and during embryogenesis in grass carp (Ctenopharyngodon idellus)

Yi-Wen Sun, Fu-Gui Li, Jie Chen, Xia-Yun Jiang, more

General and Comparative Endocrinology > 2015 > 223 > Complete > 1-8

Follistatin-like 1 (Fstl1) peptides play important roles in inhibiting myoblast proliferation and differentiation. Here, we characterized and examined the expression patterns of fstl1a and -b in grass carp (Ctenopharyngodon idellus). These genes encode 314 aa and 310 aa peptides, respectively, sharing a sequence identity of 83%. Except for the existence of the follistatin-N-terminal (FOLN) and Kazal-type...

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INFONA - science communication portal

Search results for: FU Gui

Targeting RIPK3 oligomerization blocks necroptosis without inducing apoptosis

A non‐covalent inhibitor XMU‐MP‐3 overrides ibrutinib‐resistant Btk^C481S mutation in B‐cell malignancies

Lattice-equivalence of convex spaces

Effects of forage source and particle size on chewing activity, ruminal pH, and saliva secretion in lactating Holstein cows

Nomogram for predicting preoperative lymph node involvement in patients with invasive micropapillary carcinoma of breast: a SEER population-based study

Construction of tissue‐engineered lymphatic vessel using human adipose derived stem cells differentiated lymphatic endothelial like cells and decellularized arterial scaffold: A preliminary study

An extended data envelopment analysis for the decision-making

Gill remodeling in response to hypoxia and temperature occurs in the hypoxia sensitive blunt snout bream (Megalobrama amblycephala)

An extended inequality approach for evaluating decision making units with a single output

Subcategories of the category of L-convex spaces

Enhancement of R6G fluorescence by N-type porous silicon deposited with gold nanoparticles

MiR‐21 inhibitor suppressed the progression of retinoblastoma via the modulation of PTEN/PI3K/AKT pathway

Two New Ring A‐Cleaved Lanostane‐Type Triterpenoids and Four Known Steroids Isolated from Endophytic Fungus Glomerella sp. F00244

Noncontanct detection of static humans using dual-channel SFCW bioradar

A combined external delivery optimization model for wind power and thermal power considering carbon trading and tradable green certificates based on Credibility theory

On fuzzy soft intra-regular Abel–Grassmann’s groupoids

Path Queries on Massive Graphs Based on Multi-granular Graph Partitioning

Study of the Craftwork Inpilot Scale Reactor of Hydrogen Generation from Kitchen Waste

Functional conservation and divergence of duplicated fibroblast growth factor receptor 1 (fgfr1) genes in blunt snout bream (Megalobrama amblycephala)

Two follistatin-like 1 homologs are differentially expressed in adult tissues and during embryogenesis in grass carp (Ctenopharyngodon idellus)

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