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In this paper we analyse the efficiency of two methods, rescaled range analysis and detrended fluctuation analysis, in distinguishing between coding DNA, regulatory DNA and non-coding non-regulatory DNA of Drosophila melanogaster. Both methods were used to estimate the degree of sequential dependence (or persistence) among nucleotides.We found that these three types of DNA can be discriminated by...
We recently identified approximately 1400 conserved non-coding elements (CNEs) shared by the genomes of fugu (Takifugu rubripes) and human that appear to be associated with developmental regulation in vertebrates [Woolfe, A., Goodson, M., Goode, D.K., Snell, P., McEwen, G.K., Vavouri, T., Smith, S.F., North, P., Callaway, H., Kelly, K., Walter, K., Abnizova, I., Gilks, W., Edwards, Y.J.K., Cooke,...
In a recent study, 1373 highly conserved non-coding elements (CNEs) were detected by aligning the human and Takifugu rubripes (Fugu) genomes. The remarkable degree of sequence conservation in CNEs compared with their surroundings suggested comparing the base composition within CNEs with their 5′ and 3′ flanking regions. The analysis reveals a novel, sharp and distinct signal of nucleotide frequency...
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