Search results for: Ilse Jonkers

Items from 1 to 20 out of 88 results

article

Population‐based in silico modeling of anatomical shape variation of the knee and its impact on joint loading in knee osteoarthritis

Miel Willems, Bryce A. Killen, Giacomo Di Raimondo, Christophe Van Dijck, more

Journal of Orthopaedic Research® > 42 > 11 > 2473 - 2484

Anatomical knee joint features and osteoarthritis (OA) severity are associated, however confirming causals link to altered knee loading is challenging. This study leverages statistical shape models (SSM) to investigate the relationship between joint shape/alignment and knee loading during gait in knee OA (KOA) patients to understand their contribution to elevated medial knee loading in OA. Musculoskeletal...

article

Unique shape variations of hind and midfoot bones in flatfoot subjects—A statistical shape modeling approach

Ferdia Fallon Verbruggen, Bryce A Killen, Arne Burssens, Hannelore Boey, more

Clinical Anatomy > 36 > 6 > 848 - 857

Flatfoot deformity is a prevalent hind‐ and midfoot disorder. Given its complexity, single‐plane radiological measurements omit case‐specific joint interaction and bone shape variations. Three‐dimensional medical imaging assessment using statistical shape models provides a complete approach in characterizing bone shape variations unique to flatfoot condition. This study used statistical shape models...

article

Joint kinematics alone can distinguish hip or knee osteoarthritis patients from asymptomatic controls with high accuracy

Jill Emmerzaal, Sam Van Rossom, Rob Straaten, Arne De Brabandere, more

Journal of Orthopaedic Research® > 40 > 10 > 2229 - 2239

Osteoarthritis (OA) is one of the leading musculoskeletal disabilities worldwide, and several interventions intend to change the gait pattern in OA patients to more healthy patterns. However, an accessible way to follow up the biomechanical changes in a clinical setting is still missing. Therefore, this study aims to evaluate whether we can use biomechanical data collected from a specific activity...

article

Musculoskeletal modeling‐based definition of load cases and worst‐case fracture orientation for the design of clavicle fixation plates

Sanne Vancleef, Mariska Wesseling, Jos Vander Sloten, Ilse Jonkers

Journal of Orthopaedic Research® > 40 > 9 > 2179 - 2188

Mechanical performance of clavicle fracture fixation plates is often evaluated using finite element (FE) analysis. Typically, these studies use simplified loading conditions and assume a transversal fracture orientation. However, the loading conditions and fracture orientation influence how the fracture site and thus fixation plate is loaded. In this study, a musculoskeletal model that included the...

article

Thin patient‐specific clavicle fracture fixation plates can mechanically outperform commercial plates: An in silico approach

Sanne Vancleef, Mariska Wesseling, Joost R. Duflou, Stefaan Nijs, more

Journal of Orthopaedic Research® > 40 > 7 > 1695 - 1706

Current fixation plates used to operatively stabilize clavicular fractures are suboptimal, leading to reoperation rates up to 53%. Plate irritation, which can be caused by a poor geometric fit and plate thickness, has been found to be an important factor for reoperation. Moreover, muscle attachment sites (MAS) have to be detached occasionally. To improve current surgical clavicle fracture treatment...

article

Evaluation of functional muscle anatomy scalability in the canine hind limb

Billy P. R. Dries, Ilse Jonkers, Wim Van Den Broeck, Benedicte Vanwanseele, more

Anatomia, Histologia, Embryologia > 50 > 3 > 637 - 644

In contrast to other mammals, the large variation in dog sizes is not accompanied by any significant genetic re‐organization. In order to study the relationship between body mass, limb length and the functional anatomical muscle parameters of the canine hind limb, a large dataset comprising of muscle masses, optimal muscle fibre lengths and physiological cross‐sectional area's (PCSA) were acquired...

article

Differences in foot muscle morphology and foot kinematics between symptomatic and asymptomatic pronated feet

Xianyi Zhang, Rinus Pauel, Kevin Deschamps, Ilse Jonkers, more

Scandinavian Journal of Medicine & Science in Sports > 29 > 11 > 1766 - 1773

Purpose This study aimed to determine the differences in foot muscle morphology and 3D multisegmental foot kinematics during walking between symptomatic and asymptomatic individuals with pronated feet (pronators) in a physically active population. Methods A total of 30 young physically active adults with pronated feet participated in this study, with 15 of them having recurring overuse injuries...

article

Model-based control for exoskeletons with series elastic actuators evaluated on sit-to-stand movements

Jonas Vantilt, Kevin Tanghe, Maarten Afschrift, Amber K.B.D Bruijnes, more

Journal of NeuroEngineering and Rehabilitation > 2019 > 16 > 1 > 1-21

Background Currently, control of exoskeletons in rehabilitation focuses on imposing desired trajectories to promote relearning of motions. Furthermore, assistance is often provided by imposing these desired trajectories using impedance controllers. However, lower-limb exoskeletons are also a promising solution for mobility problems of individuals in daily life. To develop an assistive exoskeleton...

article

Single finger movements in the aging hand: changes in finger independence, muscle activation patterns and tendon displacement in older adults

Nathalie Beek, Dick F. Stegeman, Ilse Jonkers, Chris L. Korte, more

Experimental Brain Research > 2019 > 237 > 5 > 1141-1154

With aging, hand mobility and manual dexterity decline, even under healthy circumstances. To assess how aging affects finger movement control, we compared elderly and young subjects with respect to (1) finger movement independence, (2) neural control of extrinsic finger muscles and (3) finger tendon displacements during single finger flexion. In twelve healthy older (age 68–84) and nine young (age...

article

The influence of maximum isometric muscle force scaling on estimated muscle forces from musculoskeletal models of children with cerebral palsy

Hans Kainz, Marije Goudriaan, Antoine Falisse, Catherine Huenaerts, more

Gait & Posture > 2018 > 65 > C > 213-220

Musculoskeletal models do not include patient-specific muscle forces but rely on a scaled generic model, with muscle forces left unscaled in most cases. However, to use musculoskeletal simulations to inform clinical decision-making in children with cerebral palsy (CP), inclusion of subject-specific muscle forces is of utmost importance in order to represent each child's compensation mechanisms introduced...

article

Functional MRI can detect changes in intratissue strains in a full thickness and critical sized ovine cartilage defect model

Deva D. Chan, Luyao Cai, Kent D. Butz, Eric A. Nauman, more

Journal of Biomechanics > 2018 > 66 > C > 18-25

Functional imaging of tissue biomechanics can reveal subtle changes in local softening and stiffening associated with disease or repair, but noninvasive and nondestructive methods to acquire intratissue measures in well-defined animal models are largely lacking. We utilized displacement encoded MRI to measure changes in cartilage deformation following creation of a critical-sized defect in the medial...

article

Virtual reality balance training for elderly: Similar skiing games elicit different challenges in balance training

Aijse W. de Vries, Gert Faber, Ilse Jonkers, Jaap H. Van Dieen, more

Gait & Posture > 2018 > 59 > C > 111-116

Virtual Reality (VR) balance training may have advantages over regular exercise training in older adults. However, results so far are conflicting potentially due to the lack of challenge imposed by the movements in those games. Therefore, the aim of this study was to assess to which extent two similar skiing games challenge balance, as reflected in center of mass (COM) movements relative to their...

article

Virtual reconstruction of glenoid bone defects using a statistical shape model

Katrien Plessers, Peter Vanden Berghe, Christophe Van Dijck, Roel Wirix-Speetjens, more

Journal of Shoulder and Elbow Surgery > 2018 > 27 > 1 > 160-166

Description of the native shape of a glenoid helps surgeons to preoperatively plan the position of a shoulder implant. A statistical shape model (SSM) can be used to virtually reconstruct a glenoid bone defect and to predict the inclination, version, and center position of the native glenoid. An SSM-based reconstruction method has already been developed for acetabular bone reconstruction. The goal...

article

Increased sensory noise and not muscle weakness explains changes in non-stepping postural responses following stance perturbations in healthy elderly

Maarten Afschrift, Friedl De Groote, Sabine Verschueren, Ilse Jonkers

Gait & Posture > 2018 > 59 > C > 122-127

The response to stance perturbations changes with age. The shift from an ankle to a hip strategy with increasing perturbation magnitude occurs at lower accelerations in older than in young adults. This strategy shift has been related to age-related changes in muscle and sensory function. However, the effect of isolated changes in muscle or sensory function on the responses following stance perturbations...

article

Hip movement pathomechanics of patients with hip osteoarthritis aim at reducing hip joint loading on the osteoarthritic side

Christophe A.G. Meyer, Mariska Wesseling, Kristoff Corten, Angela Nieuwenhuys, more

Gait & Posture > 2018 > 59 > C > 11-17

This study aims at defining gait pathomechanics in patients with hip osteoarthritis (OA) and their effect on hip joint loading by combining analyses of hip kinematics, kinetics and contact forces during gait. Twenty patients with hip OA and 17 healthy volunteers matched for age and BMI performed three-dimensional gait analysis. Hip OA level was evaluated based on plane radiographs using the Tönnis...

article

Comparison of lower limb muscle strength between diabetic neuropathic and healthy subjects using OpenSim

Alessandra Scarton, Ilse Jonkers, Annamaria Guiotto, Fabiola Spolaor, more

Gait & Posture > 2017 > 58 > C > 194-200

Diabetes neuropathy and vasculopathy are the two major complications of diabetes mellitus, leading to diabetic foot disease, of which the worst consequences are plantar ulcers and amputations. Motor impairments like joint stiffness and loss of balance are distinctive effects of diabetes and they have been extensively explored. However, while altered muscle function has been also assessed through experimentally...

article

EMG-Driven Optimal Estimation of Subject-SPECIFIC Hill Model Muscle–Tendon Parameters of the Knee Joint Actuators

Antoine Falisse, Sam Van Rossom, Ilse Jonkers, Friedl De Groote

IEEE Transactions on Biomedical Engineering > 2017 > 64 > 9 > 2253 - 2262

Objective: the purpose of this paper is to propose an optimal control problem formulation to estimate subject-specific Hill model muscle–tendon (MT-) parameters of the knee joint actuators by optimizing the fit between experimental and model-based knee moments. Additionally, this paper aims at determining which sets of functional motions contain the necessary information to identify the MT-parameters...

article

Clinical Case: Simulation-based evaluation of post-operative gait function to support clinical decision making in cerebral palsy

Lorenzo Pitto, Antoine Falisse, Tessa Hoekstra, Hans Kainz, more

Gait & Posture > 2017 > 57 > S1 > 102-103

article

Subject-specific muscle forces derived from simulations of clinical muscle strength assessments alter estimated gait functionality in children with cerebral palsy

Hans Kainz, Tessa Hoekstra, Antoine Falisse, Lorenzo Pitto, more

Gait & Posture > 2017 > 57 > S1 > 197

article

Less hip joint loading only during running rather than walking in elderly compared to young adults

Georgios Giarmatzis, Ilse Jonkers, Remco Baggen, Sabine Verschueren

Gait & Posture > 2017 > 53 > C > 155-161

Walking and running have been found to increase hip bone mass in postmenopausal women. However, the optimal speed to trigger osteogenesis is still under debate because the exact loading during different speeds is poorly characterized. Moreover, age related differences in gait kinematics/kinetics can potentially result in differences in peak hip loading, making extrapolation of results based on young...

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INFONA - science communication portal

Search results for: Ilse Jonkers

Population‐based in silico modeling of anatomical shape variation of the knee and its impact on joint loading in knee osteoarthritis

Unique shape variations of hind and midfoot bones in flatfoot subjects—A statistical shape modeling approach

Joint kinematics alone can distinguish hip or knee osteoarthritis patients from asymptomatic controls with high accuracy

Musculoskeletal modeling‐based definition of load cases and worst‐case fracture orientation for the design of clavicle fixation plates

Thin patient‐specific clavicle fracture fixation plates can mechanically outperform commercial plates: An in silico approach

Evaluation of functional muscle anatomy scalability in the canine hind limb

Differences in foot muscle morphology and foot kinematics between symptomatic and asymptomatic pronated feet

Model-based control for exoskeletons with series elastic actuators evaluated on sit-to-stand movements

Single finger movements in the aging hand: changes in finger independence, muscle activation patterns and tendon displacement in older adults

The influence of maximum isometric muscle force scaling on estimated muscle forces from musculoskeletal models of children with cerebral palsy

Functional MRI can detect changes in intratissue strains in a full thickness and critical sized ovine cartilage defect model

Virtual reality balance training for elderly: Similar skiing games elicit different challenges in balance training

Virtual reconstruction of glenoid bone defects using a statistical shape model

Increased sensory noise and not muscle weakness explains changes in non-stepping postural responses following stance perturbations in healthy elderly

Hip movement pathomechanics of patients with hip osteoarthritis aim at reducing hip joint loading on the osteoarthritic side

Comparison of lower limb muscle strength between diabetic neuropathic and healthy subjects using OpenSim

EMG-Driven Optimal Estimation of Subject-SPECIFIC Hill Model Muscle–Tendon Parameters of the Knee Joint Actuators

Clinical Case: Simulation-based evaluation of post-operative gait function to support clinical decision making in cerebral palsy

Subject-specific muscle forces derived from simulations of clinical muscle strength assessments alter estimated gait functionality in children with cerebral palsy

Less hip joint loading only during running rather than walking in elderly compared to young adults

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