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Neurons and certain kinds of endocrine cells, such as adrenal chromaffin cells, have large dense-core vesicles (LDCVs) and synaptic vesicles or synaptic-like microvesicles (SLMVs). These secretory vesicles exhibit differences in Ca2+ sensitivity and contain diverse signaling substances. The present work was undertaken to identify the synaptotagmin (Syt) isoforms present in secretory vesicles. Fractionation...
J. Neurochem. (2010) 114, 617–626.
AbstractNeurons and certain kinds of endocrine cells, such as adrenal medullary (AM) cells, have large dense‐core vesicles (LDCVs) and synaptic vesicles or synaptic‐like microvesicles (SLMVs). These secretory vesicles differ in Ca2+ sensitivity and contain different signaling substances. We have recently reported that GABA functions as a paracrine factor in rat...
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