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Objective
To evaluate the interactions of metabolic neuronal‐glial changes with the presence and hemispheric‐side of hippocampal sclerosis (HS) and its potential role in predicting pharmacoresistance in temporal lobe epilepsy (TLE).
Methods
We included structural magnetic resonance imaging (MRI) and proton magnetic resonance spectroscopy (1H‐MRS) metabolic data for 91 patients with unilateral TLE...
Purpose: To compare relative N‐acetylaspartate (NAA) measurements in temporal lobe epilepsy (TLE) patients with good response to the first trial of antiepileptic drugs (AEDs) (an important prognostic factor) to TLE patients who failed the first AED monotherapy and required further AED trials with monotherapy or polytherapy.
Methods: We studied 25 consecutive TLE patients who responded to first AED...
To compare the efficacy of medical and surgical treatment for refractory mesial temporal lobe epilepsy associated with hippocampal sclerosis (MTLE).A prospective controlled non-randomized study of 26 patients with MTLE who underwent surgical treatment and 75 patients with MTLE who underwent medical treatment between August 2002 and October 2004. All patients failed to achieve seizure control with...
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