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Sleep is a universal phenomenon in vertebrates, and its loss affects various behaviors. Independent studies have reported that sleep loss increases anxiety; however, the detailed mechanism is unknown. Because sleep deprivation increases noradrenalin (NA), which modulates many behaviors and induces patho-physiological changes, this study utilized zebrafish as a model to investigate whether sleep loss-induced...
Earlier microinjection studies showed that norepinephrine in the medial preoptico-anterior hypothalamic area (mPOAH) regulates body temperature and the action is mediated through α-1 adrenoceptors. This study was conducted to confirm if the thermosensitive neurons in the mPOAH of rats possess α-1 adrenoceptors. First, the thermosensitivity of mPOAH neurons was tested and then the effects of microiontophoretic...
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